SEXUAL HEALTH Flashcards
what are the clinical features of lymphogranuloma venereum?
- Inguinal lymphadenopathy
- Non-specific symptoms of proctocolitis (anorectal pain, rectal bleeding, mucopurulent discharge and tensesmus
- Groove sign of Greenblatt (femoral and inguinal node involvement)
- Genital elephantiasis, saxophone penis, esthiomene
- Fever, malaise, arthralgias
- Lower abdominal or lower back pain
how is lymphogranuloma venereum diagnosed?
- clinical features
- positive NAAT for chlamydia
how is lymphogranuloma venereum managed?
- oral doxycycline
- oral erythromycin in pregnant women
- pus aspiration from bubonuli to prevent rupture and sinus tract formation
what are the risk factors for developing syphilis?
- Unprotected sex.
- Multiple or anonymous sexual partners.
- Substance use.
- Transactional sex.
- Social vulnerability.
- Needle-sharing contact.
what are the clinical features of primary syphilis?
-painless genital chancre
what are the clinical features of secondary syphilis?
- A maculopapular rash.
- Condylomata lata (moist wart-like lesions).
- Buccal ulceration.
- Generalised lymphadenopathy
- Fever, headache and malaise.
what are the clinical features of tertiary syphilis?
- Loss of proprioception and vibration sensation
- Tabes dorsalis
- Argyll-Robertson pupil (accommodation but absent pupillary light reflex).
- Abdominal aortic aneurysm.
- Gummatous lesions.
what are the clinical features of congenital syphilis?
- Blunted upper incisor teeth (Hutchinson’s teeth) and mulberry molars.
- Keratitis.
- Saddle nose.
how is syphilis diagnosed?
- dark-field microscopy
- specific serological tests: EIA/TPHA/TPPA (stay positive after treatment)
- non-specific serology: VDRL/RPR (negative after treatment
how is syphilis treated?
- Offer full screening for other STIs (including HIV).
- Perform contact tracing to help limit ongoing transmission.
- Offer benzathine benzylpenicillin intramuscularly as first line management:
- Given as a single dose for primary and secondary syphilis.
- Given as three doses over 2 weeks (day 0, 7, 14) in latent late syphilis.
- Offer doxocycline for 14 days as first line treatment in patients with a penicillin allergy.
- Offer intravenous aqueous benzylpenicillin sodium for suspected neurosyphilis.
what are the clinical features of gonorrhoea in men?
- Mucopurulent or purulent urethral discharge.
- Dysuria.
- Tender epididymis in epididymitis.
- Anal discharge.
- Perianal and anal pain.
what are the clinical features of gonorrhoea in women?
- Increased or altered vaginal discharge.
- Lower abdominal and pelvic pain.
- Dysuria.
- Intermenstrual bleeding.
- Painful intercourse (dyspareunia) if the infection spreads to the endocervix.
how is gonorrhoea diagnosed?
- NAAT
- vulvovaginal swab in women
- first pass urine sample in men
how is gonorrhoea managed?
- Offer intramuscular ceftriaxone and oral azithromycin as single doses.
- Offer oral cefixime instead of intramuscular ceftriaxone if the patient refuses intramuscular injection.
- metronidazole if history of sexual abuse
what are the clinical features of genital herpes?
- Painful bilateral blisters on the external genitalia.
- Fever and malaise.
- Dysuria.
- Inguinal lymphadenopathy.
- Tingling and burning symptoms (recurrent)