Sexual Health Flashcards
What is Bacterial Vaginosis
an overgrowth of bacteria in the vagina, specifically anaerobic bacteria
What causes Bacterial Vaginosis
overgrowth of predominately anaerobic organisms such as Gardnerella vaginalis
–> fall in lactic acid producing aerobic lactobacilli resulting in a raised vaginal pH.
What anaerobic bacteria is associated with Bacterial Vaginosis
Gardnerella vaginalis (most common)
Mycoplasma hominis
Prevotella species
What risk factors are associated with Bacterial Vaginosis
- Multiple sexual partners
- Excessive vaginal cleaning
- Recent antibiotics
- Smoking
- Copper coil
How does BV present
thin, white homogenous discharge
‘fishy’ smell
asymptomatic in 50%
vaginal swab and exclude other causes of symptom
How is BV investigated?
clue cells on microscopy
Vaginal pH > 4.5
How is BV managed
oral metronidazole for 5-7 days
WHat advice should be given with metronidazole prescription and why
avoid alcohol
can cause a “disulfiram-like reaction”, with nausea and vomiting, flushing and sometimes severe symptoms of shock and angioedema.
What are complication of BV
- increase the risk of catching sexually transmitted infections
What are complication of BV in pregnant women
Miscarriage
Preterm delivery
Premature rupture of membranes
Chorioamnionitis
Low birth weight
Postpartum endometritis
What is candidiasis
thrush
vaginal infectuin with yeast if candida family
mc:candida albicans
What are risk factors of thrust
Increased oestrogen (higher in pregnancy, lower pre-puberty and post-menopause)
Poorly controlled diabetes
Immunosuppression (e.g. using corticosteroids)
Broad-spectrum antibiotics
How does thrust commonly present
Thick, white discharge that does not typically smell
Vulval and vaginal itching, irritation or discomfort
What can severe thrush lead to
Erythema
Fissures
Oedema
Pain during sex (dyspareunia)
Dysuria
Excoriation
How is thrush investigated
often Tx started empirically based on presentation
vaginal pH swab
charcoal swab w microscopy to confirm
What is the vaginal pH of thrust
< 4.5
What is the vaginal pH of BV and trichomonas
> 4.5
How can thrust treatment be delivered
- Antifungal cream (i.e. clotrimazole) inserted into the vagina with an applicator
- Antifungal pessary (i.e. clotrimazole)
- Oral antifungal tablets (i.e. fluconazole)
How is thrust treated
- A single dose of intravaginal clotrimazole cream (5g of 10% cream) at night
- A single dose of clotrimazole pessary (500mg) at night
- Three doses of clotrimazole pessaries (200mg) over three nights
- A single dose of fluconazole (150mg)
What is the name of the standard over the counter thursh treatment
Canesten Duo
contains a single fluconazole tablet and clotrimazole cream for vuvla symptoms
what should sexually active women keep in mind when using antifugal treatment
antifungal creams and pessaries can damage latex condoms and prevent spermicides from working
alternative contraceptive is required for at least five days after use.
What is Trichomonas vaginalis
a type of parasite spread through sexual intercourse
how is Trichomonas classed
protozoan, and is a single-celled organism with flagella
four flagella at the front and a single flagellum at the back
Where does Trichomonas live
lives in the urethra of men and women and the vagina of women.
What can Trichomonas increase the risk of
Contracting HIV by damaging the vaginal mucosa
Bacterial vaginosis
Cervical cancer
Pelvic inflammatory disease
Pregnancy-related complications such as preterm delivery.
How does Trichomonas vaginalis present
50% asymptomatic
Vaginal discharge
Itching
Dysuria (painful urination)
Dyspareunia (painful sex)
Balanitis (inflammation to the glans penis)
What is the characteristic description of Trichomonas vaginalis vaginal discharge
frothy and yellow-green
may have a fishy smell
What does Trichomonas vaginalis show on cervical examination
characteristic “strawberry cervix” (also called colpitis macularis)
caused by inflammation
tiny haemorrhages across the surface
How is Trichomonas vaginalis diagnosed
charcoal swab with microscopy
- Swabs should be taken from the posterior fornix of the vagina
- A urethral swab or first-catch urine is used in men.
how is Trichomonas vaginalis treated
metronidazole 500mg twice daily for 5-7 days
contact tracing needed
full sexual health screen.
sexual intercourse avoided til treated
What is a complication of trichomoniasis in pregnancy
An increased risk of premature rupture of membranes and preterm birth.
What is Chlamydia
gram-negative bacteria
intracellular organism
MC STI
significant cause of infertility
what is a intracellular organism
enters and replicates within cells before rupturing the cell and spreading to others
Is there a screening program for chlamydia
yes, National Chlamydia Screening Programme (NCSP)
screen every sexually active person under 25 years of age for chlamydia annually or when they change their sexual partner
those who test positive should have a re-test three months after treatment.
What STIs are tested in an STI screen as minimum
Chlamydia
Gonorrhoea
Syphilis (blood test)
HIV (blood test)
What two types of swabs are used in sexual health
Charcoal swabs
Nucleic acid amplification test (NAAT) swabs
What are Charcoal swabs used for
microscopy
culture
sensitivities
What is the trasnport medium for charcoal medium
Amies transport medium
What are locations of swabs for charcoal swabs in womne
endocervical swabs
high vaginal swabs (HVS).
What can charocal swabs confirm
Bacterial vaginosis
Candidiasis
Gonorrhoeae (specifically endocervical swab)
Trichomonas vaginalis (specifically a swab from the posterior fornix)
Other bacteria, such as group B streptococcus (GBS)
What does NAAT look at
DNA or RNA of the organism.
What is NAAT used to test for
chlamydia and gonorrhoea
&
Mycoplasma genitalium
What types samples are used for NAAT testing
endocervical
vulvovaginal (self taken)
and then urine
how does chlamydia present in women
majority asymptomatic
Abnormal vaginal discharge
Pelvic pain
Abnormal vaginal bleeding (intermenstrual or postcoital)
Painful sex (dyspareunia)
Painful urination (dysuria)
How does chlamydia present in men
Urethral discharge or discomfort
Painful urination (dysuria)
Epididymo-orchitis
Reactive arthritis
What are symptoms of rectal chlamydia and lymphogranuloma venereum
anorectal symptoms
such as discomfort, discharge, bleeding and change in bowel habits.
What findings would you see on examination for chlamydia
Pelvic or abdominal tenderness
Cervical motion tenderness (cervical excitation)
Inflamed cervix (cervicitis)
Purulent discharge
How is chlamydia diagnosed
NAAT
Vulvovaginal swab
Endocervical swab
First-catch urine sample (in women or men)
Urethral swab in men
Rectal swab (after anal sex)
Pharyngeal swab (after oral sex)
What is 1st line management for uncomplicated chlamydia
doxycycline 100mg twice a day for 7 days.
What is management for chlamydia in pregnancy or breastfeeding
Azithromycin 1g stat then 500mg once a day for 2 days
or
Erythromycin 500mg four times daily for 7 days
Name an Abx contraindicated in pregnancy
doxycycline
Other factors to consider in chlamydia treatment
Abstain from sex for seven days of treatment
Refer all patients to genitourinary medicine (GUM) for contact tracing and notification of sexual partners
Test for and treat any other
Provide advice about ways to prevent future infection
Consider safeguarding issues and sexual abuse
Name 3 complications of chlamydia
Pelvic inflammatory disease
Chronic pelvic pain
Infertility
Ectopic pregnancy
Epididymo-orchitis
Conjunctivitis
Lymphogranuloma venereum
Reactive arthritis
Name three pregnancy complications of chlamydia
Preterm delivery
Premature rupture of membranes
Low birth weight
Postpartum endometritis
Neonatal infection (conjunctivitis and pneumonia)
What is Lymphogranuloma Venereum (LGV)
A sexually transmitted disease caused by L1–3 serovars of Chlamydia trachomatis
affecting the lymphoid tissue around the site of infection
What primary stage LGV
a painless ulcer (primary lesion). This typically occurs on the penis in men, vaginal wall in women or rectum after anal sex
who does LGV typically affect
men who have sex with men (MSM)
What is secondary stage LGV
lymphadenitis. This is swelling, inflammation and pain in the lymph nodes infected with the bacteria
inguinal or femoral lymph nodes
What is tertiary stage LGV
inflammation of the rectum (proctitis) and anus. Proctocolitis leads to anal pain, change in bowel habit, tenesmus and discharge.
What is tenesmus
feeling of needing to empty the bowels
How is LGV treated
Doxycycline 100mg twice daily for 21 days
alt abx = Erythromycin, azithromycin and ofloxacin
What is gonorrhoea
Neisseria gonorrhoeae
gram-negative diplococcus bacteria
What type of tissue does gonorrhoea infect
mucous membranes with a columnar epithelium
such as the endocervix in women, urethra, rectum, conjunctiva and pharynx.
What increases risk of having gonorrhoea
Young, sexually active and having multiple partners
Having other sexually transmitted infections,
What ABx does gonorrhoea have resistance to
ciprofloxacin or azithromycin
How does gonorrhoea present in women
50% of women are symptomatic
Odourless purulent discharge, possibly green or yellow
Dysuria
Pelvic pain