Sexual dysfunction Flashcards
What is erectile dysfunction?
Persistent inability to attain and/or maintain an erection sufficient to permit satisfactory sexual performance.
It is a symptom, not a disease.
How are causes for erectile dysfunction categorised? Give examples for each category.
Organic
- vascular (cardiovascular, hypertension, hyperlipidaemia, peripheral arterial disease, diabetes mellitus, smoking, and obesity) -most common
- neuronal (multiple sclerosis, Parkinson’s disease, stroke, and spinal cord or central nervous system disease, diabetes mellitus, chronic kidney or liver disease, and pelvic or urological surgery)
- hormonal (hypogonadism, and hyperprolactinaemia)
Psychogenic
- lack of arousability
- disorders of sexual intimacy
- stress
- anxiety/depression
Drugs/medications
- antihypertensives
- diuretics, antidepressants
- hormonal treatments
- recreational drugs
How does erectile dysfunction present based on the category of causes?
Organic:
- Gradual onset
- Normal libido
- Presence of risk factors
Psychogenic
- sudden onset
- decreased libido
- normal self-stimulated erections
- recent major life events/problems
- changes in relationship
Medical and drug history
How is erectile dysfunction diagnosed?
Physical examination
- external genitalia
Laboratory testing
- HbA1c or fasting blood glucose (check for diabetes)
- lipid profile (CVD cause)
- morning total serum testosterone (normally serum testosterone levels are high in the morning, so if it is low that means their testosterone is always low)
- measure free testosterone (if morning total serum testosterone is low/borderline)
- repeat free testosterone with FSH, LH, prolactin (if the first free testosterone level is low/borderline)
How to manage a pt with erectile dysfunction?
Refer to urology:
- young pt with erectile dysfunction or if abnormality of penis/testicles on exam
Refer to endocrinology:
- abnormal serum testosterone, FSH, LH, or prolactin
Refer to cardiology:
- severe/unstable CVD that would make sexual activity unsafe or contraindicates PDE-5 inhibitor use (e.g. uncontrolled HTN, unstable angina, recent MI)
Refer to mental health services:
- psychogenic causes
For all pts, manage any reversible/modifiable risk factors:
- e.g. drug related factors. diabetes, HTN, etc.
Regardless of the cause for erectile dysfunction, prescribe PDE-5 inhibitor (e.g. Sildenafil, tadalafil (once daily), vardenafil, avanafil).
- contraindicated for high CV risk.
What is premature ejaculation?
This is when ejaculation occurs sooner than desired, which causes distress to either one or both partners.
What are the potential causes for premature ejaculation?
Prostatitis
Thyroid disease
Psychological distress
How do you manage a pt with premature ejaculation?
Psychosexual counselling
Topical anaesthetic
Dapoxetine
- shorting acting SSRI →this is prescribed because one of the side effect is delayed orgasm
- taken 1-3 hours prior to sexual activity
What is decreased libido?
Low sex drive causing distress
What are the causes of decreased libido?
Low testosterone
Hypothyroidism
Anxiety/depression
SSRI/SNRIs
Recreational drugs (e.g. heroin, cocaine, marijuna)
What is anorgasmia?
Persistent or recurrent delayed, infrequent or absent orgasms.
What causes anorgasmia?
Neurological disorders (e.g. Parkinson’s disease)
Previous gynaecological surgeries (e.g. scarring)
Medications (e.g. SSRIs, diuretics)
Alcohol
Smoking
Psychological and relational problems
How do you manage a pt with anorgasmia?
Treat underlying cause.
Psychosexual counselling
Oestrogen therapy
- local (suppository or cream) or systemic
- given if pt is postmenopausal and as a result experiences painful sex, so this medication will alleviate that pain and improve the ability to orgasm)
What is vaginismus?
Vaginismus is when the vagina suddenly tightens up when you try to insert something into it, causing pain during vaginal penetration (e.g. sexual intercourse, gynaecological exam, tampon insertion)
Involuntary contraction of the vaginal musculature.
What causes vaginismus?
Psychological factors:
- previous sexual trauma or adverse sexual experiences
- previous traumatic genital examination
Vestibulodynia:
- tender area at entrance of vagina due to postmenopausal oestrogen deficiency, previous genital surgery, or skin disorder.