Sexual Development Flashcards
Micro nutrient required for SRY Gene / sex related region / sex determining factor
Zn
Regulators of sex related region
Steroidogenic factor 1 (mi)
WT 1 gene
GATA 4 gene
Formation of gonads
SRY gene — ✓ SOX 9
Absence of SRY gene — ✓ WnT4, RSPO1, DAX1, Beta Catenin
Only cell type in males to express SRY gene
Sertoli cells
Marker for developing sertoli cells is
SOX 9
Prostaglandin that helps in differentiation of sertoli cells is
PGD 2
Cells that involved in blood testis barrier
cells that lie outside the blood testis barrier
Sertoli cells
Leydig cells
First ultrasound future of growing testis
Testicular chords
Testis differentiation is directed by
Somatic cells
Even if germ cells are absent, still testicular chords will develop
Sample taken for barr bodies estimation
Buccal mucosa
Testis decent is regulated by
AMH (abdominal)
Testosterone (scrotal)
insulin like factor 3
First sign of ovarian differentiation is
Absence of sertoli cells / testicular chords by 6 to 7 weeks
Ovarian primordial follicular cells identifiable after 13.5 weeks
Remnants of mullerian duct in males
Testis appendix (epididymus appendix - derivative of wolfian duct)
prostatic utricle
Gene encoding anti mullerian hormone present on which chromosome
Induced by
Hormonal markers
Chromosome 19
SOX 9 (gene marker)
Anti mullerian hormone
inhibin b
Receptors for androgen receptors located on which chromosome
Long arm of X chromosome