Sexual Development Flashcards

1
Q

Micro nutrient required for SRY Gene / sex related region / sex determining factor

A

Zn

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2
Q

Regulators of sex related region

A

Steroidogenic factor 1 (mi)
WT 1 gene
GATA 4 gene

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3
Q

Formation of gonads

A

SRY gene — ✓ SOX 9

Absence of SRY gene — ✓ WnT4, RSPO1, DAX1, Beta Catenin

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4
Q

Only cell type in males to express SRY gene

A

Sertoli cells

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5
Q

Marker for developing sertoli cells is

A

SOX 9

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6
Q

Prostaglandin that helps in differentiation of sertoli cells is

A

PGD 2

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7
Q

Cells that involved in blood testis barrier

cells that lie outside the blood testis barrier

A

Sertoli cells

Leydig cells

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8
Q

First ultrasound future of growing testis

A

Testicular chords

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9
Q

Testis differentiation is directed by

A

Somatic cells

Even if germ cells are absent, still testicular chords will develop

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10
Q

Sample taken for barr bodies estimation

A

Buccal mucosa

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11
Q

Testis decent is regulated by

A

AMH (abdominal)

Testosterone (scrotal)

insulin like factor 3

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12
Q

First sign of ovarian differentiation is

A

Absence of sertoli cells / testicular chords by 6 to 7 weeks

Ovarian primordial follicular cells identifiable after 13.5 weeks

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13
Q

Remnants of mullerian duct in males

A

Testis appendix (epididymus appendix - derivative of wolfian duct)
prostatic utricle

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14
Q

Gene encoding anti mullerian hormone present on which chromosome

Induced by

Hormonal markers

A

Chromosome 19

SOX 9 (gene marker)

Anti mullerian hormone
inhibin b

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15
Q

Receptors for androgen receptors located on which chromosome

A

Long arm of X chromosome

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16
Q

Mesonephric tubules (not ducts) in males leads to the formation of

A

Efferent tubules

17
Q

Wolfian duct remnants

A

Epooophron
Paraoophron
Gartners Duct

18
Q

Uterine endometrial thickness rapidly increase in

uterine endometrial thickness reaches its maximum in

A

Proliferative phase

secretary phase