Sex Linkage Flashcards

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1
Q

Sex-linked diseases in humans

A

recessive or mutant alleles on the X chromosome will pass on: a mother with the allele will pass on the trait to her son.
this is because the allele will be fully expressed as:
* the Y chromosome has no corresponding allele
* Y chromosome is small and carries only genes that codes for traits of manliness

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2
Q

Red-Green color blindness

A
  • caused by a recessive mutation on the X chromosome
  • much more common in men than woman
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3
Q
A
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4
Q

Haemophilia

A

one of the protiens needed for blood clotting is missing
* Haemophilia A is where clotting factor VIII is missing
* Can be fatal if not treated, and even exercise causes internal bleeding
* affects mostly males, homozygous females are rarely able to survive birth as the homozygous alleles are fatal

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