Sex Differentiation

Question 1

what is the sequential process of sex differentiation? (3)

Answer 1

1. establish genetic sex
2. translate genetic sex -> gonadal sex
3. translate gonadal sex -> phenotypic sex

Question 2

The female tract is formed from the ____ _____, connected to the _____

Answer 2

mullerian duct

ovary

Question 3

What are the components of the female reproductive tract?

Answer 3

oviduct, uterus, upper vagina

Question 4

The ___ ____ is the common primordium for external genitalia

Answer 4

urogenital sinus

Question 5

What can the urogenital sinus form into?

Answer 5

female: clitoris, vulva
male: penis, scrotum

Question 6

The male reproductive tract forms from the ___ ____, stimulated by the _____

Answer 6

wolffian duct

testis

Question 7

components of the male reproductive tract:

Answer 7

epididymis, vas deferens, seminal vesicle

Question 8

T/F: the ovaries are essential for female sex differentiation

Answer 8

false (will develop as females even with ovaries removed)

Question 9

____ are essential for male sex differentiation.

Answer 9

testes/Y chromosome

Question 10

What genetic component stimulates development of testes in males?

Answer 10

Y chromosome

Question 11

Who discovered the essential role of the testes in male sex differentiation?

Answer 11

Alfred Jost (1940s)
removed undifferentiated testes from rabbit embryo -> developed into female phenotype

Question 12

The default pathway for sex differentiation is _____

Answer 12

female