Severson Abnormal CV development Flashcards

1
Q

name 3 left to right shunts

A

atrial septal defect
ventral septal defect
patent ductus arteriosus

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2
Q

name 3 right to left shunts

A

teratology of fallot
transposition of great arteries
truncus arteriosus

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3
Q

which type of shunt makes blue babies?

A

right to left

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4
Q

what is the most common congenital heart abnormality?

A

ventricular septal defect

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5
Q

What abnormality is associated with maternal rubella during early pregnancy?

A

Patent ductus arteriosus

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6
Q

what abnormality produces a machine-like murmur?

A

PDA

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7
Q

What are the 4 defects in Tetralogy of Fallot?

A
Pulmonary stenosis
Right ventricular hypertrophy
Overriding aorta
Ventricular septal defect
e 
(PROVe)
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8
Q

What embryological defect causes a transposition of the great arteries?

A

A straight division of the bulbus cordis and truncus arteriosus (failure of normal spiraling of the aorticopulmonary septum)

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9
Q

a transposition of the great arteries is incompatible with life unless what is present?

A

A patent ductus arteriosus

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10
Q

What defect is particularly common in offspring of diabetic motheres?

A

transposition of great arteries

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11
Q

What causes a truncus arteriosus?

A

Failur of bulbar and truncal ridges to develop

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12
Q

what is a truncus arteriosus defect?

A

a common aorticopulmonary outlet, receiving blood from both ventricles

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13
Q

What are the 2 forms of a coractation of the aorta?

A

Infantile (preductal) and Adult (postductal)

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14
Q

In the postductal form, what happens?

A

constriction of aorta distal to ligamentum arteriosum

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15
Q

what happens in the preductal form?

A

narrowing of aortic segment between subclavian artery (left) and ductus arteriosus (patent)

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16
Q

What heart defects are associated with down syndrome?

A

Atrial and ventricular septal defects

17
Q

what happens in dextrocardia?

A

Heart folds left instead of right

18
Q

What does the bulbus cordis become?

A

Conus arteriosus and aortic vestibule

19
Q

What does the truncus arteriosus become?

A

gives rise to the ascending aorta and pulmonary trunk

20
Q

What developmental structures serves to divide the atrioventricular canal into R and L channels?

A

Endocardial cushions

21
Q

What do the endocardial cushions contribute to?

A

divides AV canal into R and L channels
membranous poriton of interventricular septum
closure of primary interatrial foramen

22
Q

which septum are the primary and secondary foramina associated with?

23
Q

which septum forms the foramen ovale?

24
Q

what are the bulbar and truncus ridges derived from?

A

Neural crest mesenchyme

25
what forms the membranous portion of the interventricular septum?
endocardial cushions and bulbar ridges fuse
26
what does the distal portion of the left 6th aortic arch form?
ductus arteriosus
27
what does the proximal portion of the left 6th aortic arch form?
proximal part of left pulmonary artery
28
what does the proximal portion of the right 6th aortic arch form?
proximal part of right pulmonary artery
29
what does the right 4th aortic arch form?
Right subclavian artery
30
what does the left 4th aortic arch form?
aortic arch
31
what 2 things does the aortic sac contribute to?
brachiocephalic trunk and arch of aorta
32
what drug is used to close a ductus arteriosus in newborns?
Indomethacin
33
what drug can keep a ductus arteriosus open in newborns?
PG E