Session 9 Transport of O2 and CO2 Flashcards
1
Q
CO2 production by cells
A
200 ml/min
2
Q
O2 use by cells
A
250 ml/min
3
Q
Hypoxic Hypoxia
A
- Inadequate O2 uptake into blood in lungs
- Chronic obstructive pulmonary disease
4
Q
Stagnant (ischemic hypoxia)
A
- Inadequate blood flow to an organ
- Arteriosclerosis peripheral vascular disease
5
Q
Anemic Hypoxia
A
- Inadequate blood oxygen carrying capacity
- Inactivated hemoglobin
6
Q
Histotoxic Hypoxia
A
- Interference with mitochondrial respiration
- Cyanide poisoning
7
Q
PaO2 40 = Sat of
A
75% (mixed venous blood in pulm. artery
8
Q
If sats are 90%, what is the PaO2?
A
60
9
Q
Wat is the Hb P50 point?
A
when hemoglobin is 50% saturated
PaO2 27 and Sat of 50%
10
Q
Pathological ligands of Hemoglobin
A
Ligands form covalent bonds to the ferrous iron i Hb
- Carbon Monoxide (250 times the affinity than oxygen)
- Nitric oxide binds to Hb 200,000 times more strongly
