Session 3-RMP

Question 1

What is the range of resting potential for nerve cells?

Answer 1

-50 to -75mV

Question 2

What is the SMC RMP?

Answer 2

-50mV

Question 3

What is the RMP of cardiac and skeletal muscle cells?

Answer 3

Largest

-80 to -90mV

Question 4

What is the usual intracellular conc of Na?

Answer 4

10mM

Question 5

What is the usual extracellular conc of Na?

Answer 5

145mM

Question 6

What is the usual K conc inside the cell?

Answer 6

160mM

Question 7

What is the usual K conc outside the cell?

Answer 7

4.5mM

Question 8

What is the usual Cl conc inside a cell?

Answer 8

3mM

Question 9

What is the usual Cl conc outside the cell?

Answer 9

114mM

Question 10

What channel dominates the RMP?

Answer 10

K+ channels

Question 11

What is the resting membrane potential?

Answer 11

The potential inside the cell compared to the extra cellular solution

Question 12

What does the term equilibrium potential mean for an ion?

Answer 12

The membrane potential at which there is no net movement of the ion, so conc gradient = elec gradient

Question 13

What is fast synaptic transmission?

Answer 13

When the receptor protein is itself an ion channel

Question 14

What is slow synaptic transmission?

Answer 14

When the receptor and ion channel are separate-they may be linked by G proteins or other intracellular messengers

Question 15

What is a excitatory synapse?

Answer 15

Open ligand gated channels that cause depolarisation- the inside of the cell becomes less negative creating EPSP

Question 16

Name some excitatory neurotransmitters:

Answer 16

AcH or glutamate

Question 17

What is an inhibitory synapse?

Answer 17

Ligand hated channels open causing hyperpolarisation; the inside of the cell becomes more negative creating IPSP

Question 18

Name some inhibitory neurotransmitters:

Answer 18

Glycine, GABA