Session 2

Question 1

Which of the following is true of a phase 0 trial?

A. there are cases and controls
B. efficacy is an endpoint
C. It is a representative sample
D. Participants are closely monitored and may be in a controlled environment

Answer 1

D. Participants are closely monitored and may be in a controlled environment

Question 2

Drug trials that don’t involve humans are generally described as what?

Answer 2

Preclinical

Question 2

In a phase 2 trial the endpoint is:

A. Dosage
B. Side effects
C. Physiology of the drug metabolism
D. Efficacy

Answer 2

D. Efficacy

Question 3

Which trial phase generally has the most participants?

A. Phase 2
B. Phase 1
C. Phase 4
D. Phase 3

Answer 3

C. Phase 4

Question 4

Which is the lowest trial type level where you will generally find a placebo control group or standard of care control group?

A. Phase 4
B. Phase 1
C. Phase 2
D. Phase 3

Answer 4

D. Phase 3

Question 5

When you are determining which treatment works best for blood pressure control you might use what type of study design?

Answer 5

experimental

Question 6

If you were to investigate the long term side effects of a particular treatment for prostate cancer what study design might you use?

Answer 6

observational

Question 7

Retrospective study designs:

Answer 7

Capture events from the past to a designated moment in time

Question 8

A focus is group is what type of study design?

Answer 8

qualitative

Question 9

The following study notation would be used for a randomized controlled trial.

Answer 9

ROXO; ROO

Question 10

The non-probability sampling type that utilizes inclusion criteria is:

Answer 10

judgemental

Question 11

One of the limitations of randomized sampling schemes is:

Answer 11

may miss rare events

Question 12

What type of sampling might you choose for this situation: You want to investigate whether a weight loss intervention is effective in the Somali immigrant population.

Answer 12

snowball sampling

Question 13

To ensure that you have enough individuals to draw conclusions about the health of the Hispanic population in the United State you might choose which type of sampling methodology?

Answer 13

stratified random sampling

Question 14

Threats to Internal validity include:

Answer 14

confounding

Question 15

Which value type has no order?

Answer 15

nominal

Question 16

As an investigator you are being paid to do a study for Gator-Aid and know that they would prefer positive results. One threat to the internal validity of a study might be

Answer 16

experimenter bias

Question 16

When you think about studies that involve children one of the threats to internal validity that you may need to consider is:

Answer 16

maturation

Question 17

Which value type must have a true zero value?

Answer 17

ratio

Question 17

If I measured a patient’s resting pulse 3 times within a 10 minute span this might help me calculate what?

Answer 17

intra-rater reliability

Question 17

One way to potentially reduce the threat of being unable to generalize to the affected population is to ensure

Answer 17

Correct randomization techniques are used

Question 18

Mean can be calculated for this type of data (choose all that apply)
Ordinal
Ratio
Nominal
Internal

Answer 18

Ratio Interval

Question 19

If you wanted to analyze the relationship between two ratio variables you might use what type of test?

Answer 19

Regression analysis ONLY