Session 2 Flashcards
Which of the following is true of a phase 0 trial?
A. there are cases and controls
B. efficacy is an endpoint
C. It is a representative sample
D. Participants are closely monitored and may be in a controlled environment
D. Participants are closely monitored and may be in a controlled environment
Drug trials that don’t involve humans are generally described as what?
Preclinical
In a phase 2 trial the endpoint is:
A. Dosage
B. Side effects
C. Physiology of the drug metabolism
D. Efficacy
D. Efficacy
Which trial phase generally has the most participants?
A. Phase 2
B. Phase 1
C. Phase 4
D. Phase 3
C. Phase 4
Which is the lowest trial type level where you will generally find a placebo control group or standard of care control group?
A. Phase 4
B. Phase 1
C. Phase 2
D. Phase 3
D. Phase 3
When you are determining which treatment works best for blood pressure control you might use what type of study design?
experimental
If you were to investigate the long term side effects of a particular treatment for prostate cancer what study design might you use?
observational
Retrospective study designs:
Capture events from the past to a designated moment in time
A focus is group is what type of study design?
qualitative
The following study notation would be used for a randomized controlled trial.
ROXO; ROO
The non-probability sampling type that utilizes inclusion criteria is:
judgemental
One of the limitations of randomized sampling schemes is:
may miss rare events
What type of sampling might you choose for this situation: You want to investigate whether a weight loss intervention is effective in the Somali immigrant population.
snowball sampling
To ensure that you have enough individuals to draw conclusions about the health of the Hispanic population in the United State you might choose which type of sampling methodology?
stratified random sampling
Threats to Internal validity include:
confounding
Which value type has no order?
nominal
As an investigator you are being paid to do a study for Gator-Aid and know that they would prefer positive results. One threat to the internal validity of a study might be
experimenter bias
When you think about studies that involve children one of the threats to internal validity that you may need to consider is:
maturation
Which value type must have a true zero value?
ratio
If I measured a patient’s resting pulse 3 times within a 10 minute span this might help me calculate what?
intra-rater reliability
One way to potentially reduce the threat of being unable to generalize to the affected population is to ensure
Correct randomization techniques are used
Mean can be calculated for this type of data (choose all that apply)
Ordinal
Ratio
Nominal
Internal
Ratio Interval
If you wanted to analyze the relationship between two ratio variables you might use what type of test?
Regression analysis ONLY
