Session 1 (and BL recap) Flashcards

1
Q

How many ribs are there in total?

A

24

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2
Q

Which ribs are directly attached to the sternum via their costal cartilage?

A

The first 7
- Ribs 8 to 12 are known as false ribs (3 of which share a common cartilagenous connection to sternum and last 2 are floating)

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3
Q

Pleural sacs are comprised of 2 layers. Name them:

A

Parietal and visceral serosa

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4
Q

Fluid can be drained from the pleural cavity via use of a wide bore needle. What needs to be avoided when doing this?

A

The neurovascular bundle that runs under each rib

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5
Q

The respiratory tract is made up of a conducting and respiratory portion. What is the conducting portion comprised of?

A

Nasal cavity, pharynx, larynx, trachea, primary bronchi, secondary bronchi, bronchioles, terminal bronchioles

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6
Q

The respiratory tract is made up of a conducting and respiratory portion. What is the respiratory portion comprised of?

A

Respiratory bronchioles, alveolar ducts, alveoli

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7
Q

What epithelia line the nasal cavity to the secondary bronchi?

A

Pseudostratified ciliated columnar, with presence of goblet cells

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8
Q

What epithelia line the bronchioles and terminal bronchioles?

A

Simple columnar epithelium with cilia and Clara cells, no goblet cells

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9
Q

What epithelia line the respiratory bronchioles and alveolar ducts?

A

Simple cuboidal epithelium with Clara cells

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10
Q

What epithelia line the alveoli?

A

Simple squamous

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11
Q

Does the cartilage of trachea completely surround lumen?

A

No it is C shaped - allows for the oesophagus to expand.

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12
Q

How is the cartilage of primary bronchi arranged?

A

Ring structure

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13
Q

The secondary bronchi down to bronchioles have irregular crescent plates of cartilage. True or false?

A

True

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14
Q

Bronchioles have no cartilage or glands. True or false?

A

True

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15
Q

What keeps bronchioles open?

A

Surrounding alveoli

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16
Q

What do Clara cells secrete?

A

A surfactant lipoprotein - prevents walls of bronchioles sticking together during expiration

17
Q

CF sufferers do not have the ion channel molecule CFTR - what impact does this have?

A

Chloride ion transport across membrane compromised, water does not leave epithelium to hydrate mucus -> viscous mucus less readily removed

18
Q

What type of fibres surround alveoli?

19
Q

Alveolar cells are…

A

Type I pneumocytes, type II pneumocytes

20
Q

What is the role of type I pneumocytes?

A

permit gas exchange with capillaries, predom cell type (90%)

21
Q

What is role of type II pneumocytes?

A

Produce surfactant

22
Q

What is emphysema?

A

Destruction of alveolar walls, permanent enlargement of air spaces. Alveolar walls hold bronchioles open, allowing air to leave in expiration. If damaged, difficult for lungs to empty

23
Q

What is the major factor that influences the volume of thorax?

A

Movement of diaphragm

24
Q

During inspiration, what happens to diaphragm?

A

Contracts and flattens, increasing vertical diameter of thoracic cavity -> pressure in cavity decreases and air drawn in

25
What innervates the diaphragm?
Phrenic nerve C3, C4, C5
26
Describe the movement of the chest wall during breathing, in relation to the ribs
1) Bucket handle movement: ribs move up to increase lateral dimension of thorax 2) Pump handle movement: sternum moves anteriorly and up
27
What are the 3 layers of intercostal muscles?
External, internal and innermost
28
Where is the external intercostal muscle deficient?
Anteriorly
29
Where are the internal intercostals deficient?
Posteriorly
30
Where are the innermost intercostal muscles mostly present?
Lateral aspect
31
Are intercostals important in normal tidal breathing?
No, mainly for forced ventilation
32
In what direction do the external intercostal fibres run, how do they impact ribs?
Run infero-medially (hands in pockets). When contract they pull ribs up -> muscles for inhalation (forced)
33
In what direction do the internal and innermost intercostal fibres run, how do they impact ribs?
Run at right angles to external (supero-medially to insert on rib above). Pull ribs down and backwards. -> muscles for expiration (forced)
34
There are 3 main structures that pass through diaphragm. What are they and at what level do they pass through?
1) Vena cava T8 2) Oesophagus T10 3) Aortic hiatus T12
35
An inhaled foreign body will usually go down which bronchus?
The right - more vertical and wider
36
How many lobes does the right lung have?
3
37
The intercostal neurovascular bundle runs between what layers of intercostal muscles?
Internal and innermost
38
Blood from the intercostal spaces is drained into what system?
Azygos venous system - drains into SVC