Session 1 (and BL recap) Flashcards
How many ribs are there in total?
24
Which ribs are directly attached to the sternum via their costal cartilage?
The first 7
- Ribs 8 to 12 are known as false ribs (3 of which share a common cartilagenous connection to sternum and last 2 are floating)
Pleural sacs are comprised of 2 layers. Name them:
Parietal and visceral serosa
Fluid can be drained from the pleural cavity via use of a wide bore needle. What needs to be avoided when doing this?
The neurovascular bundle that runs under each rib
The respiratory tract is made up of a conducting and respiratory portion. What is the conducting portion comprised of?
Nasal cavity, pharynx, larynx, trachea, primary bronchi, secondary bronchi, bronchioles, terminal bronchioles
The respiratory tract is made up of a conducting and respiratory portion. What is the respiratory portion comprised of?
Respiratory bronchioles, alveolar ducts, alveoli
What epithelia line the nasal cavity to the secondary bronchi?
Pseudostratified ciliated columnar, with presence of goblet cells
What epithelia line the bronchioles and terminal bronchioles?
Simple columnar epithelium with cilia and Clara cells, no goblet cells
What epithelia line the respiratory bronchioles and alveolar ducts?
Simple cuboidal epithelium with Clara cells
What epithelia line the alveoli?
Simple squamous
Does the cartilage of trachea completely surround lumen?
No it is C shaped - allows for the oesophagus to expand.
How is the cartilage of primary bronchi arranged?
Ring structure
The secondary bronchi down to bronchioles have irregular crescent plates of cartilage. True or false?
True
Bronchioles have no cartilage or glands. True or false?
True
What keeps bronchioles open?
Surrounding alveoli
What do Clara cells secrete?
A surfactant lipoprotein - prevents walls of bronchioles sticking together during expiration
CF sufferers do not have the ion channel molecule CFTR - what impact does this have?
Chloride ion transport across membrane compromised, water does not leave epithelium to hydrate mucus -> viscous mucus less readily removed
What type of fibres surround alveoli?
Elastic
Alveolar cells are…
Type I pneumocytes, type II pneumocytes
What is the role of type I pneumocytes?
permit gas exchange with capillaries, predom cell type (90%)
What is role of type II pneumocytes?
Produce surfactant
What is emphysema?
Destruction of alveolar walls, permanent enlargement of air spaces. Alveolar walls hold bronchioles open, allowing air to leave in expiration. If damaged, difficult for lungs to empty
What is the major factor that influences the volume of thorax?
Movement of diaphragm
During inspiration, what happens to diaphragm?
Contracts and flattens, increasing vertical diameter of thoracic cavity -> pressure in cavity decreases and air drawn in