Sesh 2: Electrical activity of the heart Flashcards

1
Q

What cells set the HR?

A

Automaticity of pacemaker cells in SAN.

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2
Q

With increased HR, does diastole or systole shorten?

A

Diastole…systole remains the same

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3
Q

Roughly how long is the atrio-ventricular delay, and what does this allow?

A

~ 120ms to allow time for ventricles to finish filling.

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4
Q

What are the 7 phases of the cardiac cycle?

A
  1. Atrial contraction
  2. Isovolumetric contraction
  3. Rapid ejection
  4. Reduced ejection
  5. Isovolumetric relaxation
  6. Rapid filling
  7. Reduced filling
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5
Q

What are the approximate lengths of systole and diastole in seconds?

A
Systole= 0.35 s
Diastole= 0.55 s
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6
Q

What does the P wave represent?

A

Atrial depolarisation

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7
Q

How much does atrial contraction contribute to ventricular filling?

A

The final 10%…most ventricular filling is passive.

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8
Q

What are the typical values for end- diastolic and end-systolic volume?

A
EDV= 120mL
ESV= 40 mL
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9
Q

What does the QRS complex on an ECG signify?

A

Ventricular depolarisation

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10
Q

What causes the heart sounds S1, and S2?

A
S1= closure of mitral and tricuspid valves
S2= closure of aortic and pulmonary valves
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11
Q

What does the T wave of the ECG signify?

A

Ventricular repolarisation

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12
Q

How do you calculate stroke volume?

A

EDV-ESV

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13
Q

When would you hear an aortic stenosis murmur?

A

Systole

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14
Q

When would you hear a mitral regurgitation murmur?

A

Systole

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15
Q

When would you hear a mitral stenosis murmur?

A

Diastole

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16
Q

When would you hear an aortic regurgitation murmur?

A

Diastole

17
Q

What are 2 causes of aortic stenosis?

A
  1. Degenerative senile calcification

2. Rheumatic fever

18
Q

What are 2 causes of aortic regurgitation?

A
  1. Aortic root dilation

2. Valvular damage e.g. endocarditis

19
Q

What does Quinke’s sign indicate?

A

Bounding pulse (widened pulse pressure) e.g. from aortic regurg

20
Q

What is the main cause of mitral valve stenosis?

A

Rheumatic fever