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ObGynShelf > Serum Screening in Pregnancy > Flashcards

Serum Screening in Pregnancy Flashcards

1
Q

effect on msAFP? underestimation of GA

A

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2
Q

effect on msAFP? multiple gestations

A

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3
Q

effect on msAFP? neural tube defects

A

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4
Q

effect on msAFP? abd wall defects

A

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5
Q

effect on msAFP? cystic hygroma

A

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6
Q

effect on msAFP? fetal skin defects

A

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7
Q

effect on msAFP? sacrococcygeal teratoma

A

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8
Q

effect on msAFP? decreased maternal weight

A

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9
Q

effect on msAFP? oligohydramnios

A

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10
Q

effect on msAFP? overestimation of GA

A

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11
Q

effect on msAFP? chromosomal trisomies

A

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12
Q

effect on msAFP? molar pregnancy

A

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13
Q

effect on msAFP? fetal death

A

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14
Q

effect on msAFP? increased maternal weight

A

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15
Q

1st trimester screening results? When? Trisomy 21

A

1st trimester - between 10-13wks

  1. PAPP-A: down
  2. b-hCG: up
  3. nuchal translucency: thick
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16
Q

2nd trimester screening results? When? Trisomy 21

A

2nd trimester - between 15-21wks

  1. uEstriol - down
  2. AFP - down
  3. hCG - up
  4. (inhibin A) - up
17
Q

1st trimester screening results? When? Trisomy 18

A

1st trimester - between 10-13 wks

  1. PAPP-A: down
  2. b-hCG: down
  3. nuchal translucency

18 - every test is down

18
Q

2nd trimester screening results? When? Trisomy 18

A

2nd trimester - between 15-21 wks

  1. uEstriol - down
  2. AFP - down
  3. hCG - down
  4. (inhibin A) - down

18 - every test is down

19
Q

1st trimester screening results? When? Trisomy 13

A

1st trimester - between 10-13 wks

  1. PAPP-A - down
  2. b-hCG - down
  3. nuchal translucency
20
Q

2nd trimester screening results? When? Trisomy 13

A

not available

21
Q

teratogen? masculinization of females (labial fusion)

22
Q

teratogen? fetal alcohol syndrome, IUGR, microcephaly

23
Q

teratogen? fetal hydantoin syndrome, IUGR, microcephaly, facial defects

A

phenytoin (dilantin)

24
Q

teratogen? heart and great vessel defects (Epstein)

25
teratogen? skeletal defects, limb defects
methotrexate
26
teratogen? facial defects, neural tube defects
retinoic acid
27
teratogen? skull anomalies, limb defects, miscarriage, renal tubule dysgenesis, renal failure in neonate, oligohydramnios
ACE inhibitors
28
teratogen? CNS and skeletal defects
warfarin
29
teratogen? neural tube defects
valproic acid, carbamazepine, retinoic acid
30
Condition? size>date 2/2 hydramnios, double bubble
Down syndrome w/ duodenal atresion
31
elevated msAFP w/o identifying etiology -> prognosis?
increased risk of stillbirth, IUGR, preeclampsia and placental abruption -> closely monitor

ObGynShelf (20 decks)

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