Seroneg Spondyloarthropathies, Pain syndromes, Fibromyalgia Flashcards
commonality of seronegative spondyloarthropathies
HLA-B27
seronegative means
negative for RF and lack of ANA
MS manifestations in seroneg spondyloarthropathies
back pain complaint, axial skeleton involvement, and enthesitis
list seronegative spondyloarthropathies
ankylosing spondylitis, reactive arthritis, psoriatic arthritis, and colitic arthritis
most common of the spondyloarthropathies
ankylosing spondylities
most common extra-articular symptom of ankylosing spondyloarthropathy
unilateral uveitis
BAMBOO spine may be CM that presents late in course of…
ankylosing spondylitis
what therapy is first line for ankylosing spondylitis
NSAIDS- improvement in 1-2 days
ankylosing spondylitis patients have increased risk of what fracture
spinal fracture
population affected in reactive arthritis and ankylosing spondylitis
men ages 20-40
arthropahy most commonly affecting knees, ankles, and feet after GI or GU infection
reactive arthritis
fibromyalgia is a chronic pain condition that affects what parts of body?
SOFT tissues- muscles, tendons, and ligaments. SPARES JOINTS.
diagnostic criteria for fibromyalgia
widespread pain in all 4 quadrants of body present for 3 months with axial skeleton involvement and 2. pain upon palpation of 11 or more of 18 tender sites (SYMMETRIC)
tx of fibromyalgia focuses on symptom control. education, lifestyle modification, PT, CBT. pharmocologic FDA approved include:
duloxetine, pregabalin
2 major differences between myofacial pain syndrome and fibromyalgia
- MPS pain and tenderness can be cured. 2. often just one body region in MPS affected- localized, focal pain
pain syndrome that often follows an injury or traumatic event causing soft tissue injury or fracture
complex regional pain syndrome
what can you expect to see in 3 diff stages of complex regional pain syndrome
initially- severe pain in affected area, burning, throbbing, sensitive to temp, edema. 2nd stage soft tissue edema, muscle wasting, brawny skin. 3rd stage- limited ROM
population most often seen in complex regional pain syndrome
females in 6-7 decade
autonomic testing in complex regional pain syndrome
resting sweat output, resting skin temperature, quantitiave sudomotor axon reflex test
systemic necrotizing vasculitis affecting medium sized muscular arteries causing transmural, segmental inflammation of aa.
polyarteritis nodosa
polyarteritis nodosa can affect any organ. most commonly affected is ___ and often spares ___
kidneys, lungs
diagnosis of polyarteritis nodosa
get biopsy of medium sized arteries- containing polymorphonuclear cells
polyarteritis nodosa a/w which disorders
hep b and c infection, hairy cell leukemia
patient with polyarteritis nodosa has negative ANCA test. what does this mean?
moreso confirms diagnosis. if it was positive, would look at other vasculitis disorders
