Serious and Common Adverse Effects

Question 1

What are the serious and common adverse effects of alpha-glucosidase inhibitors?

Answer 1

-abdominal pain, diarrhea, flatulence, elevated serum aminotransferase levels, elevated plasma triglycerides

Question 2

What are the serious and common adverse effects of exogenous insulin?

Answer 2

• hypoglycemia

- injection site rxn, lipodystrophy

Question 3

What are the serious and common adverse effects of insulin secretagogues?

Answer 3

• hypoglycemia
• rash, diarrhea, nausea, dizziness
• respiratory infections (meglitinides only)

Question 4

What are the serious and common adverse effects of insulin sensitizers?

Answer 4

• lactic acidosis

- diarrhea, dyspepsia, flatulence, nausea, vomiting, cobalamin deficiency

Question 5

What are the serious and common adverse effects of amylin analogue?

Answer 5

-nausea

Question 6

What are the serious and common adverse effects of incretins?

Answer 6

• GLP-1 analogues: hypoglycemia, nausea, vomiting, diarrhea, nervousness, dizziness, headache
• DPP-4 inhibitors: upper respiratory tract infection, nasopharyngitis, headache, nausea, diarrhea, mild increase in serum creatinine level

Question 7

What are the serious and common adverse effects of insulin sensitizers?

Answer 7

-heart failure, cholestatic hepatitis, hepatotoxicity, diabetic macular edema

Question 8

What are the serious and common adverse effects of diazoxide?

Answer 8

• heart failure, fluid retention, diabetic ketoacisosis, hypernatremia, bowel obstruction, pancreatitis, neutropenia, thrombocytopenia, extrapyramidal disease
• angina, hypotension, tachyarrhythmia, hirsutism, hyperglycemia, dyspepsia, dizziness, glucosuria

Question 9

What are the serious and common adverse effects of exogenous insulin?

Answer 9

-rash, nausea, vomiting