Serious and Common Adverse Effects

Question 1

What are the serious and common adverse effects of the inhibitors of cholesterol synthesis?

Answer 1

• myopathy, rhabdomyolysis, hepatoxicity, dermatomyositis

- abdominal pain, constipation, diarrhea, nausea, headache

Question 2

What are the serious and common adverse effects of the inhibitors of bile acid absorption?

Answer 2

-increase in triglyceride levels, bloating, dyspepsia, flatulence, bleeding diathesis secondary to vitamin K deficiency

Question 3

What are the serious and common adverse effects of the inhibitors of cholesterol absorption?

Answer 3

• elevated liver function tests, myopathy

- dyspepsia, arthralgia, myalgia, headache

Question 4

What are the serious and common adverse effects of fibrates?

Answer 4

• elevated liver function tests, myopathy when co-administered with a statin, arrhythmias
• dyspepsia, myalgia, gallstones, xerostomia

Question 5

What are the serious and common adverse effects of niacin?

Answer 5

• hepatotoxicity, GI bleeding

- flushing, pruritis, hyperuricemia and gout, impaired insulin sensitivity, myopathy

Question 6

What are the serious and common adverse effects of Omega-3 fatty acids?

Answer 6

• anaphylaxis

- GI discomfort, taste perversion