Sepsis week formative Flashcards

1
Q

cause of prosthetic valve endocarditis

A

strep. viridian’s

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2
Q

strep viridian’s is a gram ———-?

A

gram positive chain

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3
Q

strep viridian’s is an example of ——- haemolysis?

A

alpha

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4
Q

how is strep. viridian’s acquired?

A

intra-operatively acquired

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5
Q

what criteria is used to assess infective endocarditis?

A

duke criteria

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6
Q

enterococcus faecalis is ——– haemolysis?

A

non

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7
Q

where does e. faecalis originate?

A

gut

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8
Q

escheria species is not included in the

A

typical organisms list for diagnosing endocarditis

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9
Q

how do you diagnose infective endocardiditis

A

2 separate positive blood cultures in the absence of alternative source

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10
Q

what organisms are included in the typical organisms in the major criteria for diagnosing endocarditis? (4)

A

staph. aureus
enterococcus faecalis
viridian’s streptococci
HACEK group organisms

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11
Q

how do you diagnose C.diff?

A

stool toxin test

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12
Q

what increase the risk of C.diff infection? (4)

A

antibiotics within the preceding 3 months
proton pump inhibitors
prolonged hospitalisation
immunosuppression

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13
Q

patient visits petting zoo followed by a barbecue. she has a fever of 39 and new blood diarrhea. what is the causative organism?

A

escherichia coli

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14
Q

if patient present with e.coli gastroenteritis then we must avoid?

A

antibiotics

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15
Q

what cultures are required for e.coli gastroenteritis?

A

stool cultures

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16
Q

out of the following which is not part of sepsis 6:

  • appropriate culture
  • measure urine output
  • IV fluid resuscitation
  • measure C-reactive protein
  • Check serum lactate
A

measure C -reactive protein

17
Q

what is awn associated complication of e.coli gastroenteritis?

A

hemolytic-uraemic syndrome

18
Q

e.coli is a gram———?

A

gram negative rod/bacillus

19
Q

protracted vomiting and nausea a few hours after eating reheated rice? cause

A

bacillus crus

20
Q

how do you treat bacillus crus infection?

A

supportive managend only

21
Q

what antibiotic has o activity against anaerobes?

A

gentamicin

22
Q

what antibiotic is active against gram-positive organisms only?

A

vancomycin

23
Q

what antibiotic is active against gram negative organisms only?

A

gentamicin

24
Q
which of the following antibiotic is not a 4c antibiotic:
clarithromycin 
clindamycin 
levofloxacin 
cefazidime 
co-amoxiclav
A

clarithromycin

25
Q
which of the following drug is not a quinolone:
gentamicin 
moxifloxacin 
levofloxacin 
ciprofloxacin 
ciprofloxacin
A

gentamicin

26
Q

which drug is safe in penicillin type 1 allergy?

A

aztreonam

27
Q

what is the likely cause of sepsis in a IV drug user?

A

staph aureus

28
Q

how many blood cultures are required before antibiotics are given?

A

3 sets of blood cultures spread over one hour then start antibiotics

29
Q

pain disproportionate in the wound, causative organism?

A

necrotising fasciitis

30
Q

treatment for necrotising fasciitis?

A

urgent surgical debridement

31
Q

which antibiotic has anti-toxin effects?

A

linezolid, clindamycin

32
Q

best organism to cover staph. aureus

A

IV flucloxacillin