Sepsis Flashcards

1
Q

Does SIRS always indicate infection?

A

No

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2
Q

MAP must be below what to define septic shock?

A

65

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3
Q

Lactate must be what after fluid resus to define septic shock?

A

Greater than 2

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4
Q

How is lactate cleared from the body?

A

Liver and kidneys

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5
Q

How soon should abx be started in sepsis?

A

Within 1 hour of presentation

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6
Q

How fast should 30cc/kg of NS be given in sepsis?

A

Within first 3 hours

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7
Q

What is first line pressor in sepsis?

A

Norepi

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8
Q

What does DTTP stand for?

A

Differential time to positivity

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9
Q

What is a normal anion gap?

A

8-12

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10
Q

What are the two major reasons you can have an anion gap?

A

Increased acid load or decreased buffer load

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11
Q

What are two most likely causes of non anion gap acidosis?

A

Renal tubular acidosis, excess GI losses (ie diarrhea)

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12
Q

What are two most likely causes of anion gap acidosis?

A

Lactic acidosis, DKA

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13
Q

What is IV extravasation?

A

When IV meds leak beyond tissues

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14
Q

What two meds cause extravasation?

A

Calcium and vasopressors

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15
Q

6-D-glucan assay tests for what?

A

Fungal infections

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16
Q

Should steroids be used in sepsis?

A

No

17
Q

What is combination therapy?

A

Giving more than one abx for the same organism or class of organism

18
Q

What tidal volume should a sepsis pt be on?

A

6-8mL/kg

19
Q

Plateau pressure should be below what in septic pt?

A

Below 30

20
Q

Should septic pts have permissive hypercapnia?

A

Yes

21
Q

Fibrinogen is low or high in sepsis?

A

Low

22
Q

Fibrin degradation product is low or high in sepsis?

A

High

23
Q

Sepsis causes what type of AKI?

A

Acute tubular necrosis

24
Q

When might you give a septic pt steroids?

A

Refractory hypotension after pressors

25
Q

What does AEIOU stand for?

A

Acidemia, electrolyte abnormality, intoxication, volume overload, uremia