Sepsis

Question 1

qSOFA

Answer 1

HAT

1. Hypotension (SBP<100)
2. Altered mental status (GCS < 15)
3. Tachypnea (RR>= 22)

2 or more

Question 2

SIRS

Answer 2

1. Temp ( >= 38 OR <36)
2. HR > 90
3. RR > 20
4. PCO2 < 32
5. Leukocytosis (WBC > 1200)

Question 3

Sepsis Regimen

Answer 3

1. Measure lactate level
2. Blood cultures
3. Give ABX broad spectrum
4. Give rapid administration 30 mL/kg of crystalloid for hypotension or lactate >= 4 mmol/kg —> lactate ringer
5. Vasopressin’s (NE > epinephrine > dopamine) IF hypotensive or after fluid to maintain MAP >= 65
   - MAX NE = 0.5 mcg/kg/min —> add 2nd vasopressor
6. IF STILL HYPOTENSIVE, add corticosteroid—> hydrocortisone 50 mg IV q6h
7. IV Insulin infusion if glucose > 180 ; TARGET 140-180