sensory system Flashcards

1
Q

flow of information in the nervous system

A

Sensory neuron brings in information we have an interneuron that brings about an action

Not every sensory input needs a response

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2
Q

All stimuli represent___

A

forms of energy

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3
Q

what is necessary to convert stimulus energy into a change in the membrane potential in the nervous system

A

sensory receptor

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4
Q

all sensory pathways have four basic functions in common

A

Sensory reception

Transduction

Transmission

Perception

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5
Q

Sensory reception

A

Capture the energy of sensory signal → sense it
receptor

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6
Q

Transduction

A

Puts the sensory signal into the language of the nervous system

Changes in membrane potential

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7
Q

transmission

A

Send sensory signal to our brain

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8
Q

Perception

A

Become aware of input so that you can respond to it

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9
Q

Types of sensory receptors

A

Ionotropic sensory receptors

Metabotropic sensory receptors

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10
Q

Ionotropic sensory receptors

A

A pressure receptor
Transmembrane protein that responds to pressure by changing conformation
Push→ opens→ lets ions in (+ charges)

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11
Q

Metabotropic sensory receptors

A

Channel that open and close
Chemoreceptor and photoreceptor
Have different receiving molecules
Taste molecules & light molecules

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12
Q

process of smelling steps overview

A

Step 1: sensory reception
Step 2: transduction
Step 3: transmission
Step 4: perception

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13
Q

Step 1: sensory reception

A

There are only a few dozen taste receptor genes
Odorants enter nose
There are different chemoreceptors for different odorants
Odorant receptors are largest gene family in the genome of mammals
Odorant receptors are sensitive to specific odorants

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14
Q

Step 2: transduction

A

Odorants bind to odor receptors
Causes change in resting potential
If it changes membrane potential enough the active potential occurs

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15
Q

Step 3: transmission

A

Get signal to brain to become aware of it
Olfactory receptor cell travels to brain → olfactory bulb of brain

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16
Q

Step 4: perception

A

We perceive that smell

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17
Q
A
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18
Q

Weak vs strong smell

A

Weak smell is a lower frequency of action potentials per receptor but a strong smell is a higher frequency of action potentials per receptor
More of the molecules you are smelling are coming into your nose→ more of the odor receptors will bind to molecule and you will more frequently set off action potentials

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19
Q

how do we sense heat

A

Heat is sensed by an ion channel called TRPV1

20
Q

why do we snese heat when we eat peppers

A

Peppers have Capsaicin which binds to TRP channel and you get the sensation of hot from hot peppers
Messing with your head
Nothing is actually hot

21
Q

:
Both olfaction(taste/smell) and vision(light) use
whta kind of receptors

A

metabotropic receptors

22
Q

when we perceive vision what are we doing

A

Turning light into electrical signals

23
Q

Objects in our environment will emit light or reflect light at different wavelengths
This gives us information on

A

the chemical composition of the object → what we call color

24
Q

Specialized cells called photoreceptors are modified ___ that can detect ____. they turn light into ___

A

neurons
that can detect light
Turning light into electrical signals

25
Q

human eye composition

A

Just inside the choroid(thin layer that nourishes the neurons) are the interneurons and photoreceptors of the retina

The lens is a transparent disk of protein

In front of the lens is the clear and watery aqueous humor and behind it is the jellylike vitreous humor

The iris is a muscular structure that controls the diameter of the pupil and thus how much light enters the eye

Visual information leaves the eye and goes to the brain via the optic nerve

26
Q

The cells that are detecting light and turning light into neural signals is t

A

the rods and cones

27
Q

Light passes through ___before reaching the ____cells

A

interneurons
light detecting

28
Q

difference between rods and cones

A

Rods are more sensitive to light but don’t distinguish colors
Low light vision
Cones provide color vision
Different sensitivity to different colors

29
Q

Photoreceptors synapse onto:

which then synapse onto

A

Bipolar cells → these then synapse onto ganglion cells (link ganglion cells w photoreceptor cells)

30
Q

It is the axons of the ganglion cells that make up

A

the optic nerve(bundle of axons)

31
Q

Horizontal cells

A

involved in processing the visual image even before it goes to the brain
They sharpen edges through lateral inhibition

32
Q

Amacrine cells

A

have varied roles in visual processing such as detecting the direction of motion
Amacrine cells help detect motion

33
Q

How does the retina convert light into membrane potential that your brain can use

A

It uses light receptor molecules called rhodopsin

34
Q

Rhodopsin

A

transmembrane proteins that undergo changes in conformation as they absorb light
This sets off an event that leads to a membrane potential

consist of a protein called opsin and a light-absorbing group, 11-cis-retinal

35
Q

11-cis-retinal

A

is covalently bound in the center of the opsin molecule
When 11-cis-retinal absorbs a photon, it changes to all-trans-retinal, which changes the conformation of the opsin
This change detects light

36
Q

In rods and cones there are disks of membrane components (disks have lipid bilayer component on the outside and an internal compartments)
The transmembrane proteins that span the disks are the

A

opsin

37
Q

Retinal absorbs light and goes from ___ to ___ configuration

A

cis
trans

38
Q

Put retinal back to ___configuration so that your eye can detect light again
Enzymes in your eye do this

A

cis

39
Q

Retinal is derived from ___

A

vitamin A

40
Q

why does Consuming more vitamin A not make your eyes better

A

Once all your opsin have retinol in it it’s as good as it gets

41
Q

How do we convert light into membrane potential

A

Photoreceptor in the dark has a membrane potential of about -40

Partially depolarized in the dark
To have the membrane potential go from the more typical -70 to -40 we have a sodium current going into the cell
This channel opens and closes depending on the presence of cyclic GMP (cGMP)

42
Q

in the dark what process occurs

A

cGMP is produced and it binds to the sodium channel allowing sodium to come in
Releases glutamate
Signals to bipolar cells

43
Q

in the light what occurs

A

It activates the rhodopsin by conversion of the cis-retinal to trans-retinal
This activated the molecule transducin which activates an enzyme called phosphodiesterase

44
Q

what does phosphodiesterase do

A

This enzyme breaks cGMP to GMP
GMP doesn’t bind to the sodium channel
Closes sodium channel
Hyperpolarizes
Becomes more negative
When we absorb light our rods and cones become more negative
No glutamate released

45
Q

In signal transduction in the eye, cyclic GMP:

A

Binds to a Na+ channel and opens it