Sensory Receptors Flashcards

1
Q

What are the 5 main classes of sensory receptors found in the body?

A
  • mechanoreceptors
  • chemoreceptors
  • nociceptors
  • electromagnetic receptors
  • thermoreceptors
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2
Q

Name the 3 touch receptors in the skin

A

Pacini’s corpuscle
Meissner’s corpuscle
Merkel discs

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3
Q

Name the stretch receptor in the skin

A

Ruffini corpuscle

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4
Q

Describe pacini’s corpuscle

A
  • largest mechanoreceptor
  • onion-like encapsulation of nerve endings
  • found in deep layers of dermis and detects high frequency (40-500Hz) vibrations
  • alpha/beta fibres - glabrous and hairy skin
  • rapidly adapting due to slick viscous fluid between layers
  • low activation threshold
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5
Q

Describe meissner’s corpuscle

A
  • encapsulated nerve endings similar to Pacini’s but much smaller
  • stacks of discs interspersed with nerve endings found between dermal papillae
  • detects touch, flutter and low frequency vibrations
  • alpha/beta fibres - glabrous skin
  • rapidly adapting
  • low activation threshold
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6
Q

Describe Merkel discs

A
  • non-encapsulated nerve endings consisting of specialised epithelial cell and nerve fibres
  • found just under skin surface e.g. finger tips
  • good discrimination and detects static touch and light pressure
  • alpha/beta fibres, all skin types
  • slowly adapting and low activation threshold
  • work with Meissner’s corpuscles to detect texture
  • much better than meissner’s and pacini’s corpuscles at detecting pressure
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7
Q

what information do muscle spindles provide?

A

main proprioceptors that provide information about the state of musculature.

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8
Q

Where are muscle fibres found?

A

They lie within muscle in parallel with skeletal muscle fibres, more are found when the muscle is involved in fine motor control.

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9
Q

How are muscle spindles innervated?

A

innervated by gamma motor neurons (efferent) and group Ia and II afferent fibres. Afferents respond to muscle stretch while gamma efferent activity regulates sensitivity of the spindle.

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10
Q

What are muscle fibres made up of?

A

2 intrafusal fibres:

  • nuclear bag fibres
  • nuclear chain fibres
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11
Q

When are primary afferents activated?

A

primary afferents are associated with rate of change so are activated during contraction/stretching

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12
Q

When are secondary afferents activated?

A

secondary afferents are associated with static changes in length so whether the end muscle length is longe or shorter than the original muscle length before contraction or stretching.

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13
Q

What do GTOs provide information about?

A

The force of muscle contraction

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14
Q

How do GTOs work?

A

As the tendon is pulled, it stimulates the free encapsulated nerve endings which is what generates an action potential.

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15
Q

Which fibres are associated with GTOs?

A

Afferent Ib fibres

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16
Q

Where are GTOs found?

A

lie in tendons in series with contractile forces.

17
Q

What is the effect of having more sensory modalities in the brain?

A

more sensory modalities = higher resolution = better understanding

18
Q

What is the size of Pacini’s corpuscle receptor field?

A

Broad

19
Q

What is the size of Meissner’s corpuscle receptor field?

A

very small

20
Q

What is meant by generator potential?

A

potential caused by a stimulus to a nerve ending. generates APs in a sensory neuron.

21
Q

What is meant by receptor potential?

A

potential caused by a stimulus to a receptor cell. Affecrs amount of NT released by receptor cell onto sensory neuron.

22
Q

How is a receptor potential generated in a Pacini corpuscle?

A
  • deformation of surrounding tissue leads to changing of local membrane potential of the free nerve ending.
  • tip of the nerve ending is unmyelinated.
  • deformation results in a positive current (sodium into the nerve) leading to depolarisation.
  • this spreads along the neuron and when it spreads to the Nodes of Ranvier, an AP is generated.
  • In receptor cells, AP will lead to NT release.
  • RP induces local current flow (sodium current) which spreads along the nerve fibre.
23
Q

How are potentials amplified?

A

When the receptor potential rises above threshold in nerve fibre, AP fires.
Amplitude of RP rapidly increases at first and then less rapidly at high stimulus strength.
The more the RP rises above the threshold, the greater the AP frequency.
APs generated in the sensory nerve at a frequency directly related to the stimulus size.

24
Q

How is precise localisation of a stimulus determined?

A

Determined by:

  • size of individual nerve fibre receptor field
  • density of sensory units
  • amount of overlap in nearby receptive fields
25
Q

Describe IA fibres

A
  • myelinated
  • A-alpha
  • 12-20µm
  • 80-120m/s conduction velocity
  • e.g. somatic motor
26
Q

Describe IB fibres

A
  • myelinated
  • A-alpha
  • 12-18µm
  • 80-120m/s conduction velocity
  • e.g. GTO
27
Q

Describe II fibres

A
  • myelinated
  • A-beta
  • 5-12µm
  • 35-75m/s conduction velocity
  • e.g. touch receptors
  • A-gamma
  • 3-9µm
  • 15-30m/s conduction velocity
  • e.g. motor to spindle
28
Q

Describe III fibres

A
  • myelinated
  • A-delta
  • 1-5µm
  • 5-30m/s conduction velocity
  • e.g. crude touch
  • B
  • 1-3µm
  • 3-15m/s conduction velocity
  • eg. pre-ganglionic autonomic
29
Q

Describe IV fibres

A
  • unmyelinated
  • C
  • 0.2-1.5µm
  • 0.5-2m/s conduction velocity
  • e.g. pain and temp. sensation