seminar 2 - Hormonal Regulation of Substrate Transport Flashcards

1
Q

insulin is secreted in which specific cells?

A

beta-cells in the pancreas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

insulin stimulates the activity of what enzyme at the site of adipose tissue to 1. take up triglycerides derived from food into the tissue and 2. inhibit the release of free fatty acids into the blood.

A
  1. lipoprotein lipase 2. Hormone-sensitive lipase
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The post-absorptive state refers to the condition where a person has just consumed a meal and is absorbing the macronutrients

A

false

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How much is the energy potential that is stored in liver glycogen?

A

around 400 kcal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

A patient has a blood glucose concetration at the end of the 2h OGTT of 10.9 mmol/L. In what category does this patient fall in terms of blood glucose homeostasis?

A

impaired glucose tolerance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Glucagon triggers a(n) [1] in blood glucose concentrations. The [2] is the responsible organ for this effect. The condition in which this metabolic response occurs is in the [3]

A
  1. Increase 2. Liver 3. Postabsorptive state
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

from a hormonal perspective, why is there a change in concentration?

A

insulin suppresses breakdown of TAGs into fatty acids so high insulin results in less breakdown of TAGs so theres a lower conc of NEFAs after a meal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

when blood glucose concentrations rise between 2 measurements what does this mean for the rate of appearance (a) and disappearance (d)?

A

rate of a is greater than the rate of d

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

when blood glucose concentrations drop between 2 measurements what does this mean for the rate of appearance (a) and disappearance (d)?

A

rate of d is greater than the rate of a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

when blood glucose concentrations are the same between 2 measurements what does this mean for the rate of appearance (a) and disappearance (d)?

A

rate of d is equal to the rate of a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly