semi-conservative replication Flashcards

1
Q

why is DNA replication described as semiconservative?

A
  • strands from original DNA molecule act as templates
  • new DNA molecule contains 1 old strand and 1 new stand -> specific base pairing enables genetic material to be conserved accurately
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2
Q

explain the role of DNA helicase in semiconservative replication

A

breaks H-bonds between base pairs to form 2 single strands, each of which can act as a template

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3
Q

how is a new strand formed during semiconservative replication?

A
  • free nucleotides from nuclear sap attach to exposed bases by complementary base pairing
  • DNA polymerase joins adjacent nucleotides on new strand in a 5’ to 3’ direction via condensation reactions to form phosphodiester bonds
  • H-bonds reform
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