semi-conservative replication Flashcards
1
Q
why is DNA replication described as semiconservative?
A
- strands from original DNA molecule act as templates
- new DNA molecule contains 1 old strand and 1 new stand -> specific base pairing enables genetic material to be conserved accurately
2
Q
explain the role of DNA helicase in semiconservative replication
A
breaks H-bonds between base pairs to form 2 single strands, each of which can act as a template
3
Q
how is a new strand formed during semiconservative replication?
A
- free nucleotides from nuclear sap attach to exposed bases by complementary base pairing
- DNA polymerase joins adjacent nucleotides on new strand in a 5’ to 3’ direction via condensation reactions to form phosphodiester bonds
- H-bonds reform
