Semester 1 Review

Question 1

What are the three stages of blood clotting?

Answer 1

1) vasoconstriction
2) primary hemostasis (platelets and vWF)
3) secondary hemostasis (clotting factors)

Question 2

What part of the CBC/Fe panel tells you if it is a microcytic or macrocytic anemia?

Answer 2

The MCV
Mean cell volume
Its the average volume (size) of RBCs

Question 3

What is the definition of anemia?

Answer 3

Low RBC, low Hbg, or Hct

Question 4

What controls the production of RBC?

Answer 4

Erythropoeitin secreted via kidneys

Question 5

Reticulocyte

Answer 5

Is a good indication of how the bone marrow is responding to low RBC

Question 6

What does a retic count of greater than 2 mean?

Answer 6

That the bone marrow is reacting and the RBC loss is due to bleeding or hemolysis

Question 7

What does a retic count less than 2 mean?

Answer 7

Failure of the bone marrow to respond to low RBC either from the absence of epo production, nutrients, or damaged marrow

Question 8

High indirect bilirubin represents what?

Answer 8

Hemolysis

Question 9

What 4 lab results point to hemolysis?

Answer 9

High indirect bilirubin
High retic count
High LDH
Hemoglobinuria

Question 10

What is MCHC?

Answer 10

Mean cell hemoglobin

Average Hgb per RBC

Question 11

What is MCH?

Answer 11

Mean cell Hgb
Average Hgb for ALL cells

This can tell you if its hypochomic or hyperchromic

Question 12

How is the Mentzer index calculated?

Answer 12

MCV/RBC

Question 13

What does a Metzner index of greater than 13 suggest?

Answer 13

Fe deficiency anemia

<13 suggests thalassemia trait