Semantic Impairments

Question 1

Locus of Semantic Dementia

Answer 1

Bilateral atrophy and hypometabolism of the (inferior and lateral) anterior temporal lobes

Question 2

Locus of Stroke Aphasia

Answer 2

Left posterior temporal-inferior parietal regions (temperoparietal region) AND LIPC (Left Inferior Prefrontal Cortex)

Question 3

Which illness shares the same locus/deficits as Semantic Dementia?

Answer 3

Herpes simplex encephalitis

Question 4

Is Semantic Dementia sensitive to cueing effects?

Answer 4

No

Question 5

Do patients with Semantic Dementia display sensitivity to frequency/familiarity effects?

Answer 5

Yes

Question 6

Do patients with Semantic Dementia display consistency effects?

Answer 6

Yes

Question 7

Do patients with SD display refractoriness?

Answer 7

No

Question 8

What type of semantic errors do patients with SD make? (for example, in picture naming tasks)

Answer 8

Coordinate (E.g. Cat>Dog) and Superordinate (E.g. Animal>Dog)

Question 9

What type of semantic errors do patients with Stroke Aphasia make?

Answer 9

They also make Associative errors (E.g. Foot>Shoe)

Question 10

Are patients with Semantic Aphasia sensitive to cueing effects?

Answer 10

Yes

Question 11

Do patients with Semantic Aphasia display refractoriness?

Answer 11

Yes

Question 12

What are the characteristics of Semantic Dementia?

Answer 12

Fluent speech, intact phonology and grammar but impairments with semantic knowledge

Question 13

What are the characteristics of Semantic Aphasia?

Answer 13

Varies dependent upon the type of Aphasia: can affect any one of the four modalities but likely affects all to some degree.

Question 14

Name the study which produced a computational model of the brain and damaged it in the anterior temporal regions, producing the same deficits seen in SD

Answer 14

Rogers et al, 2004

Question 15

Name the study which demonstrated that the LIPC is likely responsible for semantic selection as opposed to retrieval

Answer 15

Thompson-Schill et al, 1997