Select Narrow Therapeutic index drugs Flashcards
1
Q
Amikacin (traditional dosing) - Peak, Trough
A
Peak: 20-30mcg/mL; Trough: <5mcg/mL
2
Q
Carbamazepine
A
4-12mcg/mL
3
Q
Digoxin for Afib
A
0.8-2.0ng/mL
4
Q
Digoxin for HF
A
0.5-1.0ng/mL
5
Q
Gentamicin (traditional dosing) - Peak, trough
A
Peak: 5-10mcg/mL; Trough: <2mcg/mL
6
Q
Lithium
A
0.6-1.2mEq/L (can be as high as 1.5mEq/L for acute symptoms)
7
Q
Phenobarbital - Adults, children
A
Adults: 20-40 mcg/mL; Children: 15-30mcg/mL
8
Q
Phenytoin
A
10-20mcg/mL
9
Q
Procainamide, NAPA
A
4-10mcg/mL, 15-25mcg/mL
10
Q
Tacrolimus
A
5-20mcg/mL (varies based on concomitant drugs and type of transplant)
11
Q
Tobramycin (traditional dosing)
A
Peak: 5-10mcg/mL, Trough: <2mcg/mL
12
Q
VPA
A
50-100mcg/mL (can be high as 150mcg/mL in some patients)
