Seizure Pharm Flashcards
1
Q
Tx for partial, including secondarily generalized seizures.
A
Lamotrigine (Na channel)
Carbamazepine (Na channel)
Levetiracetam (unknown)
Oxcarbazepine (Na channel, K+ channel, Ca2+ channel)
2
Q
Primary generalized tonic-clonic seizures.
A
VPA (everything)
Lamotrigine (Na channel)
Levetiracetam (unknown)
3
Q
Absence in adults.
Absence in kids.
A
Adults: VPA (everything) or
ETX (T-type Ca channel)
Kids: ETX (T-type Ca channel)
4
Q
Atypical absence, myoclonic, atonic seizures.
A
VPA
LAM
LEV
5
Q
Where do phenobarbitol and benzodiazepine work?
What do they do when they get there?
A
GABA receptor- but different sites
* enhance GABA activity*
Barbs- prolong opening time of Cl- channel
Benzos- shift GABA dose-response curve to left.
6
Q
Infantile spasms?
A
ACTH
