Seizure meds MOA Flashcards

1
Q

Na channel inhibitors

A
Phenytoin
Carbamazepine
Oxcarbazepine
Eslicarbazepine
Lamotrigine
Lacosamide
Zonisamide
Fosphenytoin
Valproic Acid (multiple MOA)
Topiramate (multiple MOA)
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2
Q

GABA potentiation

A
Phenobarbital
Clobazam
Vigabatrin
Clonazepam
Diazepam
Lorazepam

Valproic acid (multiple MOA)
Topiramate (multiple MOA)
Propofol (multiple MOA)

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3
Q

SV2A modulation

A

Levetiracetam

Brivaracetam

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4
Q

NMBA inhibition

A
Valproic acid (multiple MOA)
Propofol (multiple MOA)
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5
Q

T-type calcium channel inhibition

A

Ethosuximide

Valproic acid (multiple MOA)

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6
Q

Glutamate (AMPA) inhibition

A

Perampanel

Topiramate (multiple MOA)

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7
Q

Calcium channel inhibitors

A

Gabapentin
Pregabalin

Topiramate (multiple MOA)

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8
Q

Valproic acid (multiple MOA)

A
  1. GABA potentiation
  2. NMBA inhibition
  3. Na channel inhibition
  4. T-type calcium channel inhibition
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9
Q

Topiramate (multiple MOA)

A
  1. GABA potentiation
  2. AMPA inhibition
  3. Na channel inhibition
  4. Calcium channel inhibition
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10
Q

Propofol (multiple MOA)

A
  1. GABA potentiation

2. NMDA inhibition

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