Seizure drugs

Question 1

What is the indication for diazepam?

Answer 1

Prolonged convulsions of 5+ minutes or 3+ in an hour and currently convulsing
Eclamptic convulsions lasting over 2-3 mins or convulsions
Symptomatic cocaine toxicity

Question 2

What is the action of diazepam?

Answer 2

CNS depressant, anticonvulsant and sedative

Question 3

What are the contraindications for diazepam?

Answer 3

Hypersensitivity

Question 4

What is the initial dose of diazepam?

Answer 4

IV - 10mg
Rectal - 20mg

Question 5

What is the repeat dose of diazepam?

Answer 5

IV -10mg
Rectal - 10mg

Question 6

What is the dose interval for diazepam?

Answer 6

10 minutes

Question 7

What is the maximum dose for diazepam?

Answer 7

30mg

Question 8

What are the indications for midazolam?

Answer 8

Prolonged convulsions of 5+ minutes or repeated convulsions 3+ in an hour and currently convulsing. Convulsions continued 10 min after initial dose

Question 9

What is the action of midazolam?

Answer 9

Short acting benzodiazepine, anxiolytic, sedative and anticonvulsant

Question 10

What are the cautions for midazolam?

Answer 10

Enhanced side effects with alcohol or other sedative drugs, can leads to respiratory depression/arrest - more likely in children, adults over 60 and those with chronic illnesses