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Therapeutics (Fall 2024) > Seizure > Flashcards

Seizure Flashcards

1
Q

What is a seizure?

A
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2
Q

What is epilepsey

A
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3
Q

What is the definition of epilepsy now?

A
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4
Q

Why are we trying to using the term antiseizure?

A

Not all people who have seizures and epilepsey (Antiepileptic drug), no longer anticonvulsant medication because not all people who expeirence seizures get convulsions

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5
Q

What is the risk of recurrence for seizures?

A
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6
Q

What causes seizures?

A

Anything that disturbs the normal functioning of the cerebral cortex can cause seizures and if this abnormality is enduring it can result in epilepsy

The metabolic disorders, referrence to the inherited issues.

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7
Q

What types of infection can lead to seizures>

A

Any infection that leads to increase inflammation etc…

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8
Q

What immune conditions can cause seizures?

A

Auto immune disease that disrupt the brain

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9
Q

What is the patho for seizures?

A

Alteration of voltage gated ion channels

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10
Q

What is an example of excitatory seizure activity?

A

Where we take away alcohol, glutamate is super high and leads to increased neurotransmission

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11
Q

What is hypersynchrony?

A
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12
Q

Many of the ASMs target ____ of the possible causes of seizures.

A

1+

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13
Q

What is the impact on patients lives?

A
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14
Q

What are the various classification of seizures?

A
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15
Q

Not all ASMs treat all seizures types and some drug can _______ when used for the incorrect seizure type

A

worsen seizures

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16
Q

What are the three classifications of seizures?

A

Focal, generalized, unknown

17
Q

What are focal seizure classifications?

A

Originiate within networks limited to one hemisphere

18
Q

What are the seizure type: generalized

A

Orginaites at some point within and rapidly engaging, bilaterally distributed netowkrs

19
Q

What are the seizure type: unknown

A

Reflects the difficulty to classify unwitnessed seizures and those that occur while the patient is asleep

20
Q

Tonic seizure

A
21
Q

Atonic Seizure

A
22
Q

For focal onset what is the next classificaiton?

A

Aware or impaired awareness

23
Q

What is the most common type of seizure class?

A

focal onset 70%

24
Q

Many of the drugs that we use are based on the ))) language

A

Old

25
Q

What are focal seizures?

A
26
Q

What are generalized seizures?

A

Ca

27
Q

Can focal transition to generalized?

A

Yes

28
Q

What is Status epilepticus?

A
29
Q

Any seizure that does not stop wihtin 5 minutes should be _____ as ___

A

treated, impending status epilepticus

30
Q

Seizures lasting longer tahn 5 minutes or repetitive seizures are

A

treated as SE to prevent consequences and increase response to tx

31
Q

What is generally the on demand BZD given in adults?

A

Lorazepam 1-2mg sublingual

32
Q

In pediatrics what is generally used to reduce risk of progression to status epilepticus?

A
33
Q

In infants what is generally used to reduce risk of progression to status epilepticus?

A

Rectal diazepam

34
Q

What is Post-ictal symptoms?

A

Ella confused why she is in a suitcase

35
Q

What is the diagnosis for epilepsey?

A

Physical/neuro
History***
Diagnostics like EG CT MRI labwork

Rule out that seizure is not drug induced

36
Q

What medication classes can increase Sz risk?

A
37
Q
A

Therapeutics (Fall 2024) (11 decks)

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