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Biología molecular > Segundos mensajeros > Flashcards

Segundos mensajeros Flashcards

1
Q

Tipos de ligando

A

Esteroides
Aminoacidos
Gases
Eicosanoides

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2
Q

Como se sintetiza el AMPc?

A

Adenil ciclasa

A partir de ATP

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3
Q

Como se degrada el AMPc?

A

AMPc fosfodiesterasa

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4
Q

Cinasa dependiente de AMPc

A

PKA

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5
Q

EPAC

A

Proteina de intercambio activada directamente por AMP

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6
Q

Que fosforila la PKA?

A

El factor de transcripcion CREB

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7
Q

Metabolismo

Expresión de genes

División celular y crecimiento

Diferenciación celular

Neurotransmisión

A

Funciones AMPc

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8
Q

Como se sintetiza el GMPc?

A

Guanilil ciclasa

A partir de GTP

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9
Q

Como se degrada el GMPc?

A

GMPc fosfodiesterasa

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10
Q

Cinasa dependiente GMPc

A

PRKG

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11
Q

Productos de la fosfolipasa C al romper a Fosfatidillinositol 4,5 bifostfato PIP2

A

IP3
Diacilglicerol

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12
Q

Producto de fosfatidilinositol 3 cinasa al fosforilar a fosfatidillinositol 4,5 bifostfato PIP2

A

PIP3

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13
Q

Producto de PIP3

A

PKB (proteina cinasa B) o AKT

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14
Q

Inhibe apoptosis de proteinas

A

AKT1

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15
Q

Señalizacion de insulina, transporte de glucosa

A

AKT2

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16
Q

Factores de transcripcion de PKB (uso)

A

Metabolismo celular
Sintesis de proteinas

17
Q

Proteina que se une al calcio

A

Calmodulina

18
Q

Activadas por receptores tirosin-cinasa y receptores acoplados a proteinas G

(general)

A

Ras, Raf, MAPK

19
Q

Proteinas que se encuentran unidas a GDP (inactivo) o GTP (activo) activadas por receptores tirosion-cinasa y receptores acoplados proteinas G

A

Ras

20
Q

Cinasa activadas tambien por tirosin-cinasa y receptores acoplados a proteinas G que promuve proliferacion celular y diferenciacion

A

Raf

21
Q

Cinasa serina/treonina activadas por receptores tirosion-cinasa y receptores acoplados proteinas G

A

MAPK

22
Q

Apoptosis, inflamacion, proliferacion y produccion de citoquinas

A

Vía MAPK

23
Q

Cinasa janus Signal traducers and activators of transcription

A

JAK /STAT

24
Q

Que activa DAG?

A

PKC

Biología molecular (10 decks)

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