Segars: Introduction to Pharmacology Flashcards
What is pharmacodynamics?
- how the DRUG affects the body
- MOA
What is Pharmacokinetics?
- How the BODY affects the drug
- ADME
What is ADME
- absorption
- Distribution
- metabolism
- elimination
What is a prodrug
- the inactive form
- gets transformed into active compound
Pharmacotherapeutics
-study of the appropriate use of meds to effectively treat or prevent disease and manage sx
Pharmacogenetics
-genetic impact on drug metabolic or handling processes which can affect individual responses to drugs
Pharmacoeconomics
-field of study utilizing scientific and economic methods to evaluate and compare value between therapies
Pharmacoepidemiology
-field of study that applies epidemiological principles and methods to study the uses and effects of medications on large populations
What does pharmaceutical equivalence mean?
- same ingredients
- same dosage form
- same strength
What is a pharmaceutical alternative?
- SAME DRUG!
- different form or salt form
Therapeutic equivalence
-must be pharmaceutically equivalent and have the same therapeutic effect and safety profile
What is bioequivalence
- similar rate and extent of absorption
- 80-125% of reference product
When is the generic drug “just as good” as the other one?
-when it is pharmaceutical, therapeutically, and bio- equivalent!
Which generics are the good drugs to give?-
-the A rated ones… not B rated
among the scheduled/controlled drugs, what FDA classification means it’s ok?
- C-V
- the higher the number, the more ok it is
What are the 9 legal requirements of prescriptions?
- name/address of prescriber
- name/address of patient
- date prescription was written
- name and strength of medication
- directions for use (use the abbrevs)
- quantity to be dispensed
- number of refills allowed
- prescriber’s signature
- Prescriber’s DEA number (2 letter, 7 digit)
convert 1 kg to lbs
-1kg=2.2 lbs!
microgram
-1/1000 of a mg
tbsp to tsp
- 1tbsp= 3 tsps
- 15mL
ounces to tsp and tbsp and mL
- 30 mL
- 2 tbsps
- 6 tsp
quart
- 946 mL
- 2 pints= 1 quart
Gallon to liters
- G= 3.79L
- 4 quarts
- 8 pints