Seegars - Antipsychotics Flashcards
High potency typical antipsychotics
Fluphenazine, haloperidol
Low potency typical antipsychotics
Chlopromazine
Tx for EPS d/t antipsychotics
Anticholinergics - diphenhydramine, benztropine, trihexyphenidyl
SAE to clozapine
Agranulocytosis
Atypical antipsychotics over time can cause
Metabolic syndrome - st gain, hyperglycemia, hyperlipidemia
Atypicals with risk of stroke
Olazapine, paliperidone, risperidone - greater risk in elderly with dimensia
Antipsychotics that can be admin as long-acting injections
Haloperidol, fluphenazine, risperidone, olanzapine, aripiprazole, paliperidone
atypical agents that are also partial agonists at D2/D3 and 5HT1A receptors
Aripiprazole, brexpiprazole
antipsychotic used to tx recurrent suicidal behavior
clonzapine
typical antipsycotic agents
haloperidol, chorpromazine, fluphenazine
3 common endings of atypical antipsychotics
-piprazole, -apine, -idone
general MOA of antipsychotics
block D2 postsynaptic receptors
atypical agents have a greater propensity to block _____ than typicals
5HT receptors
atypical that also potently blocks NERT
noquetiapine
low potency typical antipsychotics
chlorpomazine, thiridazine
high potency typical antipsychotics
fluphenazine, haloperidol
muscarinic antipsychotic SE’s
dry mouth, const, urinary retention, blurred vision, sedation
alpha adrenergic antipsychotic SE’s
orthostatic hypotension, impotence
histamine antipsychotic SE’s
sedation
women, enderly, and pts on anti-arrhythmics taking antipsychotics are at a higher risk of
QT prolongation/ECG changes
