Sedatives/ Anxiolytics

Question 1

BENZODIAZEPINE OD

Answer 1

R
- Usual

R
- Generally benign sedation and ataxia, even in kids
- Concern is with:
–> Alprazolam
–> Coingestant sedatives

S
ANTICIPATE:
- Symptoms within 1-2 hours (sleepy, ataxic)
- Sedation –> coma
- Resp depression
- HypoTN only in massive dose

-SUPPORT:
- Mainstay

I
- 12-lead, BGL, parac (delib)
- UDS if diagnostic diff.

D
AC: No. Good outcomes with supportive.

E
No.

A
FLUMAZENIL
–> Paediatric OD when airway compromised
(0.01-0.02mg/kg every minute)
–> Try and avoid in adult OD (risk of dependence/ seizure). Only if airway compromise, and can’t intubate….
(0.1-0.2mg/kg every minute)
–> Monitor for resedation (90mins)

D
OBSERVE 2 hours