Sedatives Flashcards
Action of Versed
- Hypnotic, amnesia, sedative, anticonvulsant
- Potent but short acting, 3 to 4 times more potent than diazepam
- Has no effect on pain
Midazolam classification
Tranquilizer, benzodiazepine
Versed onset of action
IV – 1.5 to 5 minutes
IN – 2 to 6 minutes
IM- 15 minutes
Versed duration of action
2 to 6 hours
Indication of Versed
- Premedication prior to cardioversion
- Acute anxiety
- Premedication prior to paralytics
- Post intubation sedation
- Seizures
Contraindication of Versed
- Narrow angle glaucoma
2. Shock and alcoholic coma
Use with caution Versed
Resuscitative equipment available
Monitor vitals for respiratory depression
Accentuated by narcotics and alcohol
Dosage and administration of Versed
Adult: 2mg increments to max dose of .1 Mg/kg or 10mg (which ever is less) IV/IO/IM
Give 1/2 dose if > 60 years old
Pediatric: .2mg/kg IM or .1mg/kg IV slowly over two minutes and no greater than 2mg increments, not to exceed 5mg
Adult and pediatric IN for seizures: .2mg/kg of 5mg/ml concentration
Adverse reaction of Versed
- Hypotension, respiratory depression, apnea, laryngospasm, bronchospasm, bradycardia, tachycardia, PVCs
- May decrease ICP in head injury patients
- Nasal burning for 30 to 45 sec post IN
Versed referenced in protocol
Traumatic emergencies for seizure, crush injury
Cardiac emergencies
Medical emergencies, actively seizing
RSI
Behavioral emergencies, combative patient
Classification of diazepam
Anticonvulsant, anti-anxiety, sedative
Action of diazepam
Depress central nervous system
Onset of action for diazepam
1-5 min, peak action 5-10 min
Duration of action for diazepam
15–60 min
Indications for diazepam
- Seizure secondary to head trauma or DTs
- Status epilepticus
- Prior to pacing, cardioversion, and RSI. For relief of anxiety & tension and amnesia
- Envenomation’s resulting in muscle spasm
- Severe anxiety
Contraindication of diazepam
Interaction with other CNS depressants
Use with caution for diazepam
Elderly
Inadequate pulmonary function
Liver and or kidney disease
History of drug addiction
Dosage and administration for diazepam
Adult: 2-10mg IV/IM/IO
Ped: 0.2mg/kg IV/IO in increments no> than 2mg, Max dose 10mg. Wait 1-2 min between doses to observe effect. Rectally, 0.5mg/kg to max dose of 20mg. Wait at least five min between doses. Contact MBCH for repeat dose
Adverse reaction for diazepam
CNS depression, ataxia, transient hypotension, respiratory depression
Venous thrombosis and phlebitis at injection site
Reference and protocol for diazepam
Traumatic emergencies, seizures, Burns
Cardiac emergencies
Medical emergencies, ALOC if actively seizing
Environmental emergencies, envenomations
Behavioral emergencies, combative patients
RSI
