Sedative/ Hypnotic &Anxiolytics Flashcards

1
Q

1- All of the following are properties of sedative/ hypnotic in sleep except :

A- Decrease the latency of sleep onset.
B- Decrease the duration of REM
C- NO tolerance
D- Decrease the duration of slow wave sleep

A

C

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2
Q

2- phenobarbital is

A- Ultrashort acting barbiturates
B- Short acting barbiturates
C- Long acting barbiturates

A

C

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3
Q

3- the most anxiolytic and sedative hypnotic drugs used are :

A- Barbiturates
B- Benzodiazepines
C- Opioids

A

B

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4
Q

4- A property of BZDs is :

A- Respiratory depression
B- Analgesic
C- Anaesthetic

A

C

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5
Q

5- more selective drug in panic attacks :

A-Diazepam
B- Clonazepam
C- Midazolam
D- Alprazolam

A

D

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6
Q

6- All the following are side effects of Ramelteon except :

A- Dizziness
B- Nausea
C- Somnolence
D- Fatigue

A

B

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7
Q

7- antidote of Benzodiazepines:

A- Flumazenil
B- Physostigmine
C- Phytonadione

A

A

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8
Q

8- zolpidem is BZDs acting on BZD1 receptor

A- True
B- False

A

B

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9
Q

9- Flumazenil is competitive antagonist at BZDs receptor antagonizing BDZs & zolpidem

A- True
B- False

A

T

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10
Q

10- Sedative/hypnotic wouldn’t induce sleep at high doses resemble normal sleep

A- True
B- False

A

B

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11
Q

11- Disadvantages of Buspirone are

A

1- Delayed onset
2- doesn’t treat insomnia or panic attacks

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12
Q

12- Why drug therapy with sedative-Hypnotics should be started with small oral doses for limited period ?

A

To avoid drug abuse & dependence.

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13
Q

13- Why termination of drug therapy with Sedative-Hypnotic should be gradual ?

A

To avoid withdrawal syndrome

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14
Q

14- Insomniac patients who complain of early morning awakenings & who require anxiolytic effect during the day should receive a short acting BZD

A- True
B- False

A

B ( long acting BZD as Diazepam )

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15
Q

15- Acute anxiety treated by antidepressants

A- True
B- False

A

False (chronic)

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16
Q

16- Buspirone is useful in panic disorder

A- True
B- False

A

False, panic disorder requires highly potent drugs as Alprazolam

17
Q

17- Lorazepam has no active metabolites thus preferred In liver dysfunction

A- True
B- False

A

A

18
Q

18- Side effects of Buspirone:

A

A- Nausea
B- headache dizziness

19
Q

19- Ultra short acting BZDs :

A- Alprazolam
B- Lorazepam
C- Midazolam
D- Diazepam

A

C

20
Q

20- One of the following is adverse effect of BZDs

A- Ataxia
B- fatigue
C- headache

A

A

21
Q

21- Toxicity of BZDs are :

A

A- prolonged sleep
B- respiratory & cardiovascular depression