Sedation and Rapid Sequence Intubation Flashcards

1
Q

______ is a big reason we are going to sedate a patient along with intubation

A

pain

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2
Q

Perception, Expression, & Tolerance of pain are influenced by:

A

Psychological factors
Social factors
Cultural factors

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3
Q

patients pain level is __________________, it can be influenced by psychological social and cultural factors.

A

what they say it is

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4
Q

_____ can cause more pin (previous hospital visit where pain wasn’t managed),

A

anxiety

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5
Q

Unrelieved pain:

Inadequate sleep
Exhaustion
Anxiety
Disorientation
Agitation
PTSD
Post Intensive Care Syndrome
____________________
____________________

A

Can increase morbidity
Can increase length of stay

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6
Q

patients in the ICU (50%) get some kind of PTSD — this is called ___________________________

A

post intensive care syndrome

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7
Q

Getting enough _____________ is even more important to our physical and mental health than diet and exercise.

A

quality sleep

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8
Q
  1. Quality sleep becomes more difficult as we _____, but it’s still as important.
A

age

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9
Q

Two-thirds of adults throughout all developed nations fail to obtain the recommended eight hours of nightly sleep.

The shorter your sleep, the shorter your ___________.

Human beings are theonly species that will deliberately deprive themselves of sleepwithout legitimate gain.
The physical and mental impairments caused by one night of bad sleep dwarf those caused by an equivalent absence of food or exercise.

______ is the single most effective thing we can do to reset our brain and body health each day.

A

life span, Sleep

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10
Q

Sleep:

Restores the brain’s capacity for ______
makes room for new memories.
The more sleep spindles an individual has at night, the greater the restoration of overnight learning ability come the next morning.
Is like clicking the “save” button.
Protects newly acquired information against forgetting.
Transports memories from a temporary storage hold (hippocampus) to a more secure, permanent home (the cortex).
Sleep clears out the cache of short-term memory for the new imprinting of facts, while accumulating an ever-updated catalog of past memories.
Sleep salvages memories that appeared to have been lost soon after ______.

A

learning, learning

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11
Q

Sleep:

Vehicle accidents caused by ______ exceed those caused by alcohol and drugscombined.
After being awake for ____________, people who were sleep-deprived were as cognitively impaired as those who were legally drunk.
Students who stay up late cramming for tests experience a 40% deficit in their ability to make new memories relative to those that get a full night of sleep.
Sleep is neurological sanitation.
Getting too little sleep across the adult life span will significantly raise your risk of developing ____________ disease.

A

drowsy driving, nineteen hours, Alzheimer’s

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12
Q

Adults 45+ who sleep ___ hours are 200% more likely to have a ________________________ compared to those sleeping 7-8 hours.
In the Northern Hemisphere, the switch to daylight savings time in March results in most people losing an hour of sleep opportunity. When viewed across the millions of daily hospital records, this seemingly trivial sleep reduction comes with a frightening spike in heart attacks the following day.
The less you sleep, the more you are likely to _____.
Chronic sleep deprivation is one of the major contributors to ____________.
Insufficient sleep is linked to ______.
Short sleep causes the body to deplete muscle mass and ______.

A

<6, heart attack or stroke, eat, type 2 diabetes, obesity, retain fat

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13
Q

Men who suffer from sleep disorders (sleep apnea and snoring) have significantly lower levels of _______________.
Your immune response suffers after a single night of reduced sleep

A

testosterone

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14
Q

Throughout the course of their residency, one in five medical residents will make a sleepless-related medical error that causes significant, liable harm to a patient.
One in twenty will ____ a patient due to a lack of sleep.
Medical errors are the ___________ of death among Americans after heart attacks and cancer. Sleeplessness undoubtedly plays a role in those lives lost.
If you are about to undergo an elective surgery, you should ask how much sleep your doctor as had.
One cannot “learn” how to overcome a lack of sleep and develop resilience.

A

kill
third-leading cause

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15
Q

anxiety:

Apprehension-Agitation-Autonomic arousal-Fearful withdrawal
Prolonged state of apprehension in response to a real or perceived fear
Assessed as whatever the patient reports
Inter-related with ____
Relationship between _____ and anxiety is cyclical

A

pain, pain,

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16
Q

Pain and anxiety __________ of one another
Pain leads to anxiety. Anxiety enhances pain. Further pain worsens anxiety, etc.

A

exacerbate

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17
Q

anxiety is high when we don’t get enough sleep

__________ –do as many things that you can for them at a time

patients anxiety is whatever they say it is

strong correlation between pain and anxiety –our job to do pharmacological and __________ interventions

A

bundle your care, nonpharmacological

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18
Q

anxiety contributes to pain perception by:

Activating pain ______
Altering the cognitive evaluation of pain
Increasing aversion to pain
Increasing the report of pain
Creating feelings of ______

Leads to greater __________, especially in patients with cardiovascular disease.

A

pathways, powerlessness, morbidity and mortality

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19
Q

Anxiety is escalated by:

Noise of alarms, equipment, personnel
Bright ambient lighting
Excessive stimulation from inadequate pain relief
Frequent ______
Repositioning
Lack of mobility
Uncomfortable __________
Sleep deprivation
Circumstances leading to admission

A

assessments, room temperatures

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20
Q

Pain:

Results from a signal cascade within the neurological network
______: comes from irritation or damage to the nervous system. bones muscles, soft tissue.
_______: Diffuse, poorly localized, often referred. from organs and blood vessels.
Is a ______ mechanism because it stimulates movement away from the thing causing harm

A

Somatic pain, Visceral pain, protective

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21
Q

Negative effects of pain & anxiety

Associated with a 10 year increase in mortality rate after PCI
__________ secondary to pain and anxiety is stressful because the rapid breathing increases patient effort

A

Hyperventilation

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22
Q

Negative effects of pain & anxiety:

Causes feelings of breathlessness that lead to __________ with the ventilator
_________________ can be a result of dyssynchrony

A

dyssynchrony, Alveolar damage

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23
Q

Physiological responses to pain and anxiety:

______
Cool extremities
Diaphoresis
__________________
Increased cardiac output
Increased______ production
Pupillary ______ (mydriasis)
Nausea
Pallor and flushing
Sleep disturbance
Tachycardia
Tachypnea
_______

A

Constipation, Hypertension, glucose, dilation, Urinary Retention

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24
Q

2 years post ICU stay study:

59% of patients still experienced general anxiety, depression, and PTSD
35% had PTSD symptoms during follow up
50 % had taken ___________ drugs
40 % required psychiatric treatment since hospital discharge

A

psychiatric

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25
Q

Agitation risk factors:

Extreme anxiety
Moderate to severe pain
Delirium
Mechanical ventilation
Smoking habits

Fun fact: Agitation increases days spent on _____

A

ventilator

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26
Q

for nurses :

avoid ______ when possible.

counseling can be good for nurses,

pet therapy can be good, art therapy can also be helpful,

A

drugs and alcohol

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27
Q

Results of delirium:

Sleep disturbances
Abnormal psychomotor activity
Emotional disturbances
If untreated, is a predictor of negative clinical outcomes in critically ill patients
Increased _____ , ______, ______
Long-term cognitive impairment consistent with _________

A

mortality
Increased length of stay
Increased cost of care

dementia-like state

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28
Q

American College of Critical Care Medicine & Society of Critical Care Medicine Comprehensive Guidelines:

Evidence based practice
Patient centered protocols
Treat ____
Treat ______
Consider Sedation
Focus on delirium, immobility and sleep disruption in critically ill patients
Recommends:
1. Validated monitoring instruments
2. Nonpharmacological AND pharmacological interventions
3. Coordinating care around the patient’s goals

A

Pain, Agitation,

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29
Q

What does the ABCDEF bundle mean?

A

Awakening and Breathing Coordination
Delirium monitoring and management
Early exercise and mobility (rehabilitation)
Family Engagement
AND SLEEP

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30
Q

What does the ABCDEF bundle result in?

A

Less time on mechanical ventilation
Less delirium
Early mobilization
Decreased length of stay in the critical care unit and the hospital

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31
Q

Pain assessment:

Thorough assessment
Ongoing assessment
Reassessment
Documentation of interventions and responses
Involves collecting the patient’s report and behavioral markers
Should identify and treat possible causes of anxiety too such as _______________________________________________, pain and withdrawal from drugs.

A

hypoxemia, hypoglycemia, hypotension

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32
Q

What is PQRST ?

A

provocation, quality, radiation, severity, and timing

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33
Q

What scale is used on patients who cannot communicate in the ICU?

A

Critical Care Pain Observation Tool (CPOT)

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34
Q

What is the max score on the CPOT?

A

8

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35
Q

What scale do we used for sedated patients?

A

CPOT

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36
Q

Goal: Maintain ______ effective sedation to achieve ______ duration of mechanical ventilation

A

lightest, shorter

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37
Q
  1. accumulation of medication
  2. increased hospital stay
  3. pneumonia
  4. delayed ventilator weaning
  5. immobility
A

consequences of too much sedation

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38
Q
  1. Agitation
  2. Inappropriate use of paralytics
  3. Increased metabolic demand
  4. Increased risk of myocardial ischemia
A

consequences of not enough sedation

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39
Q

check _____ to see how well gut is absorbing food.

A

residuals

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40
Q

Rass scale is how we determine if our patients are ______ appropriately.

A

sedated

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41
Q
  1. 10 point scale ranging from ______ (4+) to _____________ (-5)
  2. Patient is assessed for _____ seconds
  3. Light sedation: _________
  4. Light sedation is the ____________
A

combative
unarousable
30-60
(-2) up to (+1)
ideal range

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42
Q

_______ tells us if we need to turn sedation up or down.

A

rass

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43
Q

What is another scale beside the CPOT and RASS, what is its scale?

A

Sedation agitation scale. 1 (unrousable) to 7 (dangerous agitation)

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44
Q

Records spontaneous brain activity that comes from cells on the surface of the brain
Converts EEG signal into a numeric score 0-100 (100 = fully awake)

A

BIS monitor

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45
Q

________________ noninvasive, objective analysis on the level of the patient’s wakefulness

A

BIS provides

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46
Q

BIS has strong correlation with ?

A

RASS score

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47
Q

BIS BISPECTRAL INDEX SCORE
____= Full consciousness
_____=Deep sedation
___= Complete EEG supression

A

90
40-60
0

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48
Q

Measurement of pupil size and reactivity to light
Uses an infrared camera to noninvasively monitor pupil diameter changes
Allows for assessment of ______

A

opiod administration.

Pupil dilation reflex (pupillometry)

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49
Q

______ = significant central opiod effect, which indicates that the patient would be better treated with:
Regional block
Ketamine
Other non-opiod therapy

A

Pain + LOW PDR

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50
Q

Ketamine:

Anesthetic
Interrupts association pathways of the brain selectively
Provides sensory blockade
Can be used for _____ or _____

A

PAIN, RSI

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51
Q

What is ketamine dose for pain?

A

IV bolus 0.2-0.3 mg/kg with mas of .35 mg/kg

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52
Q

What is the RSI dose for ketamine?

A

2 mg/kg

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53
Q

What is a common side effect of ketamine?

A

nightmares

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54
Q

What does the RSI dose of ketamine do?

A

inhibit breathing

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55
Q

UNDERSTAND THAT THIS MAY MAKE YOUR PATIENT GOOFY, HALLUCINATION, DISORIENTED, INCREASES BP AND ICP

A

ketamine

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56
Q

Ketamine: NMDA side effects

A

Can cause emergence reaction
anacute confusion state during recovery from anesthesia; patients with ED may present with disorientation, hallucination, restlessness, and purposeless hyperactive physical behavior
Hypertension
Respiratory Depression
Apnea
Nausea and vomiting
Anaphylaxis
Can increase ICP

57
Q

not appropriate for patients with already high ICP

A

ketamine

58
Q

Ketamine: Nurse Job

A

Monitor BP, HR, respiratory status
Protect the airway (from vomiting most likely)
Use very cautiously in patients with head injury as this can increase ICP
Provide safety in the event of unpleasant hallucinations, confusion, excitement
Educate patient and family before administration
PROVIDE SAFETY

59
Q

one person will monitor the patient and they will be assigned this job this is all they do, will just watch the monitor.

A

When RSI dose of ketamine is given

60
Q

______ are the only ones who can do moderate sedation

A

physicians

61
Q

provide safety: ABC, bed rails up, intervening for ABC issue, main goal is to keep patient safe.

A

honestly everything, but for ketamine

62
Q

always use the ___ dose vial

A

smaller

63
Q

Changing or fluctuating mental status
Inattention
Disorganized thinking
Altered levels of consciousness
Elderly patients more at risk

A

delirium

64
Q

45-87% of patients who are critically ill experience this
If untreated may result in longer ventilation and stay

A

delirium

65
Q

_______________: agitated, combative, disoriented, at elevated risk for injury because of altered thought processes and behaviors. May experience hallucinations, delusions, paranoia

A

Hyperactive Delirium

66
Q

_______________: “quiet __________” that often goes undiagnosed
theyre super confused and no one really knows bc theyre quite

A

Hypoactive Delirium, delirium

67
Q

___________: have features of both delirium

A

Mixed Delirium

68
Q

Non-pharmacological therapy for pain, anxiety, and delirium

A

Orient with calendars and clocks
Engage the family
Role model to the family reassurance
Role model avoiding arguing with confused patients
Teach family how to do passive ROM
Teach family how to help with hygiene
Bring in pictures and keepsakes from home to improve environment
Let the patient face the window
Conceal equipment

69
Q

what are alternative therapies ?

A

guided imagery, music therapy, essential oils and aromatherapy, animal therapy,

70
Q

Improved pulmonary function
Earlier ambulation
Earlier mobilization
Decreased stress response
Lower catecholamine concentration (pressors)
Lower oxygen consumption
Improved outcomes

A

appropriate pain management results

71
Q

__________: Fastest onset. Shortest duration
doesn’t typically lower bp really fast.
don’t slam –-__________,
give over ______ minutes

A

FENTANYL. chest wall rigidity, 2-5

72
Q

_________: Longer duration. May cause hypotension or prolonged sedation in patients with renal insufficiency
decreased O2 demand
increases vasodilation
give over 2-5 minutes
if given too fast –__________

A

MORPHINE, causes vomiting
lowers BP

73
Q

_______: Prepare to apply o2
have a nasal canula nearby
works really well, but it wears off really quickly

A

HYDROMORPHONE

74
Q

if youre giving IV push of opiods or benzos –give over _________

A

2-5 minutes

75
Q

What is a typical IV dose of fent?

A

50-100 mcg q1 -2 hours IV is a normal dose

76
Q

what are side effects of fent?

A

Bradycardia, Hypotension, CHEST WALL RIGIDITY, muscle rigidity, constipation, itching

77
Q

Is more pressure-protective than other opiods

A

fent

78
Q

occasionally used for sedation, but mostly for pain, what happens if you give it too fast?

A

chest wall rigidity

79
Q

How fast should you give morphine?

A

Give SLOWLY over 4-5 min

80
Q

what can morphine’s side effects be?

A

resp depresion
n/v

81
Q

what are nursing interventions for morphine?

A

Apply o2 PRN
Monitor vitals and intervene PRN
Use lower doses in older adults

82
Q

what is an appropriate dose of morphine for an adult?

A

2-10 mg

83
Q

What is the dose for hydromorphone?

A

0.2-1 mg IV q2-3 hours for severe pain

84
Q

What are the side effects of hydromorphone?

A

Respiratory depressionHypotension

85
Q

What are nursing care interventions for hydromorphone?

A

Prepare to give o2-Give SLOWLY (2-5 minutes)-Note that the potency of hydromorphone to morphine is 7:1-Avoid giving to opiod naïve patients
Antidote: Naloxone/Narcan

86
Q

Patient controls when med is given
Special infusion pump
Patient pushes a button for a prescribed bolus of pain medication
Safe and effective pain management

A

PCA pump

87
Q

What is the antidote for benzodiazepines?

A

flumazenil

88
Q

What scales do you use to assess sedative benzos?

A

SAS or RASS

89
Q

What are benzos used for?

A

sedation, anxiety, seizures

90
Q

what is the dose for midazolam?

A

0.01-0.05 mg/kg over 2-3 min IVP

0.02-0.1 mg/kg/hr continuous infusion

91
Q

What are the side effects of benzos?

A

CNS depression
hypotension, resp depression
paradoxical agitation

92
Q

What can happen if we give them flumazenil?

A

seizures

93
Q

propofol is known as ?

A

jackson juice, milk of amnesia, or diprivan

94
Q

propofol tubing has to be changed ?

A

q 12 hrs bc of bacteria

95
Q

what do you need to monitor with propofol?

A

triglyceride levels

96
Q

propofol:

Rapid increases in administration rate can cause ______________________! ***

A

cardiorespiratory depression. only increase doses every 3-5 minutes bc of this

97
Q

Can NOT be given IVP by a nurse in OK but it CAN be managed on a pump.

A

propofol

98
Q

what do you need to monitor for with propofol?

A

CNS depression, respiratory depression, hypotension, fever, sepsis, hyperlipidemia

99
Q

propofol:

Initial infusion rate _____________ for 5 min

A

5mcg/kg/min

100
Q

Loss of sensation, consciousness and reflexes -Used for MAJOR surgery requiring complete muscle relaxation

A

general anesthesia

101
Q

Loss of sensation WITHOUT loss of consciousness -used for a particular part of the body

A

local anesthesia

102
Q

during moderate sedation you will never give a _______

A

paralytic

103
Q

ALWAYS GIVE ___________ BEFORE ____________ WITH THE EXCEPTION OF IF THEY ARE COMBATIVE

A

SEDATIVE, PARALYTIC

104
Q

anesthesia:

______ is the #1 priority in all situations
Titrate meds CAREFULLY and SLOWLY
______________ can deteriorate quickly with sedation and should be monitored closely for cardiac complications
With the use of anesthesia, ALWAYS inquire about ________________.
damages CNS

A

Airway patency, Elderly individuals, malignant hyperthermia

105
Q

what is the reversal for malignant hyperthermia?

A

dantrolene

106
Q

THIS IS A LIFE THREATENING EMERGENCY
INHERITED MUSCLE DISORDER requiring screening questions

A

malignant hyperthermia

107
Q

treatment for malignant hyperthermia

A

STOP SURGERY
Give Dantrolene (this is a muscle relaxer)
What is the dose and how fast is it given? (look this up)
100 % o2
Get ABGs
Infuse ICED saline
Cooling blankets
Indwelling temperature sensing foley catheter

108
Q

dantrolene:

What is the dose and how fast is it given?

A

at least 1 mg/kg. up to 10 mg. fast,

109
Q

anesthesia that does not result in loss of consciousness

A

moderate sedation

110
Q

Client can *respond to verbal stimuli*retains protective reflexes (gag reflex) *is easily arousable *maintains own airway

A

moderate sedation

111
Q

Which of the following procedures would be appropriate under moderate sedation?

Cholecystectomy
Breast Augmentation
Closed reduction of the wrist
Open fracture reduction of the right femur

A

closed reduction of the wrist

112
Q

(ONLY GIVE MEDICATIONS THAT CAN ___________________ IN THE PRESENCE OF A PROVIDER SKILLED AND QUALIFIED IN INTUBATION. NEVER GIVE THIS WITHOUT THIS PERSON IN THE ROOM!)***

A

REMOVE RESPIRATORY DRIVE

113
Q

What is required during moderate sedation?

A

Consent prior to medications
Continuous monitoring
An RN who has no other responsibilities at that time must have the job to solely monitor the patient
Crash cart with emergency medications, airway and ventilator equipment, defibrillator, IV supplies (should already have a minimum of one patent IV)
100% o2 source and administration supplies such as airways manual BVM and suction equipment
ECG monitor and display, non invasive blood pressure monitor, pulse ox, thermometer, stethoscope, ETCO2, A PROVIDER CAPABLE OF INTUBATING*****
ETco2: Measures the exhaled oxygen with each breath and is an indicator of _____ _________.

114
Q

ETco2: Measures the exhaled oxygen with each breath and is an indicator of _____ _________.

A

adequate ventilation

115
Q

End tidal Co2 (ETC02) is an indicator of:

How well a patient is sedated
How well a patient is breathing
How much o2 is attached to hemoglobin molecules
The rhythm of the heart

A

how well a patient is breathing

116
Q

you can ventilate them with ______________ so that there is actually a seal. to go ahead and intube, yes you will probably need to remove ___________.

A

dentures, dentures

117
Q

1 focus is ____________________ status

Never leave the patient. If you are designated to ___________ you may NOT perform any other role. *** Look up moderate sedation on the OK BON website. This is specifically listed.

A

monitor the patient, cardiac and respiratory

118
Q

anti-emetic:
Ondansetron/Zofran
-decreases risk of ____________
-Can result in _____________

A

aspiration,
prolonged qt interval (arrhythmia)

119
Q

anti-emetic:

Phenergan/Promethazine
-decreases risk of ________
-includes sedation
-high rate of ____________________

A

aspiration, necrosis with extravasation.,

120
Q

Metoclopramide/Reglan
-decreases the risk of ___________
-enhances _______________
-Fun fact: often will make patient feel ______________________________

A

aspiration
gastric emptying
the desire to leave immediately

121
Q

Phenergan/promethazine is given how ?

A

IM ONLY -Cancause phlebitis and tissue necrosis in the vein

122
Q

___________
-found in your crash cart
-used for bradycardia or to decrease the risk of bradycardia during surgery
-blocks the muscarinic response to ________________ by decreasing salivation, bowel movement, and GI secretions
-Slows motility of the GI tract
-Decrease saliva, perspiration, and gastric and pancreatic secretions
-Decreases the risk of aspiration

A

Atropine , acetylcholine,

123
Q

What condition is atropine contraindicated to give with?

A

glaucoma

124
Q

atropine:
Preanesthesia (To Decrease Salivation/Secretions) dose

A

IM IV Subcut (Adults): 0.4–0.6 mg 30–60 min preop.

125
Q

atropine PALS ACLS use:

Bradycardia

dose

A

V (Adults): 0.5–1 mg; may repeat as needed every 5 min, not to exceed a total of 2 mg (every 3–5 min in Advanced Cardiac Life Support guidelines)

126
Q

Toxicity and Overdose: atropine

If overdose occurs, ____________ is the antidote.

A

physostigmine

127
Q

What are s/s of anticholingeric toxidrome?

A

Altered mental status, mydriasis (blindness), red flush skin, hot dry skin, dry mucous membranes

128
Q

Atropine may cause dry mouth and difficulty voiding. t/f

A

true

129
Q

Primary use of atropine is:

To slow the GI tract
To prevent patients from needing to go to the bathroom during moderate sedation
To dry sections and keep heart rate above 60
To alleviate pain

A

to dry secretions and keep HR >60

130
Q

Are neuromuscular blocking agesnts used in moderate sedation?

A

no. you NEVER GIVE NMBA WITHOUT SEDATION

131
Q

__________________:
-has a short half-life (less than ______), is either off or on, can cause ______
-avoid use of this in ______ patients. Why?

A

Succinylcholine
10 min
hyperkalemia
dialysis

132
Q

HYPERKALEMIA IS A BIG DEAL –HIGH POTASSIUM LEVELS, BRAIN INJURY PATIENTS ARE ALSO NOT GREAT CANDIDATES FOR THIS DRUG,

A

succinylcholine

133
Q

Rocuronium
-has longer half life (about ______)
BETTER FOR ____________________________________
TYPICALLY NOT USED FOR THE NORMAL PEOPLE BC IT LASTS ______ MINUTES, IF YOU DON’T GET THE AIRWAY YOU MIGHT HAVE TO BAG THEM FOR ____________.

A

30 min, DIALYSIS AND BRAIN INJURY PATIENTS, 30, 30 MINUTES

134
Q

Vecuronium:
-has a long half life (about an _____)
-is often used during _____________
IS MORE LONG TERM, NOT USED for _____
WHEN PATIENTS CODE –___________________________ –THIS IS GIVEN TO PREVENT SHIVERING

A

hour
therapeutic hypothermia
RSI
THERAPEUTIC HYPOTHERMIA

135
Q

Paralytics are also known as NMBA
Paralytics are NOT given during _____________
One nurse must be dedicated to the monitoring of the patient while he or she is undergoing the procedure
Common drugs given for moderate sedation include ___________________________________

A

moderate sedation
Ketamine, Diprivan/propofol and versed/midazolam

136
Q

paralytics are aka NMBA: _____________________________

A

succintylcholine, rocuronium, vecuronium

137
Q

versed –decreases ____, -it will affect your _______________ almost every time

A

bp, blood pressure

138
Q

etomidate is __________ and _____________________succinylcholine for RSI

A

~20 mg, 100 mg