Sedation and Rapid Sequence Intubation Flashcards

1
Q

______ is a big reason we are going to sedate a patient along with intubation

A

pain

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2
Q

Perception, Expression, & Tolerance of pain are influenced by:

A

Psychological factors
Social factors
Cultural factors

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3
Q

patients pain level is __________________, it can be influenced by psychological social and cultural factors.

A

what they say it is

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4
Q

_____ can cause more pin (previous hospital visit where pain wasn’t managed),

A

anxiety

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5
Q

Unrelieved pain:

Inadequate sleep
Exhaustion
Anxiety
Disorientation
Agitation
PTSD
Post Intensive Care Syndrome
____________________
____________________

A

Can increase morbidity
Can increase length of stay

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6
Q

patients in the ICU (50%) get some kind of PTSD — this is called ___________________________

A

post intensive care syndrome

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7
Q

Getting enough _____________ is even more important to our physical and mental health than diet and exercise.

A

quality sleep

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8
Q
  1. Quality sleep becomes more difficult as we _____, but it’s still as important.
A

age

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9
Q

Two-thirds of adults throughout all developed nations fail to obtain the recommended eight hours of nightly sleep.

The shorter your sleep, the shorter your ___________.

Human beings are theonly species that will deliberately deprive themselves of sleepwithout legitimate gain.
The physical and mental impairments caused by one night of bad sleep dwarf those caused by an equivalent absence of food or exercise.

______ is the single most effective thing we can do to reset our brain and body health each day.

A

life span, Sleep

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10
Q

Sleep:

Restores the brain’s capacity for ______
makes room for new memories.
The more sleep spindles an individual has at night, the greater the restoration of overnight learning ability come the next morning.
Is like clicking the “save” button.
Protects newly acquired information against forgetting.
Transports memories from a temporary storage hold (hippocampus) to a more secure, permanent home (the cortex).
Sleep clears out the cache of short-term memory for the new imprinting of facts, while accumulating an ever-updated catalog of past memories.
Sleep salvages memories that appeared to have been lost soon after ______.

A

learning, learning

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11
Q

Sleep:

Vehicle accidents caused by ______ exceed those caused by alcohol and drugscombined.
After being awake for ____________, people who were sleep-deprived were as cognitively impaired as those who were legally drunk.
Students who stay up late cramming for tests experience a 40% deficit in their ability to make new memories relative to those that get a full night of sleep.
Sleep is neurological sanitation.
Getting too little sleep across the adult life span will significantly raise your risk of developing ____________ disease.

A

drowsy driving, nineteen hours, Alzheimer’s

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12
Q

Adults 45+ who sleep ___ hours are 200% more likely to have a ________________________ compared to those sleeping 7-8 hours.
In the Northern Hemisphere, the switch to daylight savings time in March results in most people losing an hour of sleep opportunity. When viewed across the millions of daily hospital records, this seemingly trivial sleep reduction comes with a frightening spike in heart attacks the following day.
The less you sleep, the more you are likely to _____.
Chronic sleep deprivation is one of the major contributors to ____________.
Insufficient sleep is linked to ______.
Short sleep causes the body to deplete muscle mass and ______.

A

<6, heart attack or stroke, eat, type 2 diabetes, obesity, retain fat

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13
Q

Men who suffer from sleep disorders (sleep apnea and snoring) have significantly lower levels of _______________.
Your immune response suffers after a single night of reduced sleep

A

testosterone

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14
Q

Throughout the course of their residency, one in five medical residents will make a sleepless-related medical error that causes significant, liable harm to a patient.
One in twenty will ____ a patient due to a lack of sleep.
Medical errors are the ___________ of death among Americans after heart attacks and cancer. Sleeplessness undoubtedly plays a role in those lives lost.
If you are about to undergo an elective surgery, you should ask how much sleep your doctor as had.
One cannot “learn” how to overcome a lack of sleep and develop resilience.

A

kill
third-leading cause

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15
Q

anxiety:

Apprehension-Agitation-Autonomic arousal-Fearful withdrawal
Prolonged state of apprehension in response to a real or perceived fear
Assessed as whatever the patient reports
Inter-related with ____
Relationship between _____ and anxiety is cyclical

A

pain, pain,

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16
Q

Pain and anxiety __________ of one another
Pain leads to anxiety. Anxiety enhances pain. Further pain worsens anxiety, etc.

A

exacerbate

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17
Q

anxiety is high when we don’t get enough sleep

__________ –do as many things that you can for them at a time

patients anxiety is whatever they say it is

strong correlation between pain and anxiety –our job to do pharmacological and __________ interventions

A

bundle your care, nonpharmacological

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18
Q

anxiety contributes to pain perception by:

Activating pain ______
Altering the cognitive evaluation of pain
Increasing aversion to pain
Increasing the report of pain
Creating feelings of ______

Leads to greater __________, especially in patients with cardiovascular disease.

A

pathways, powerlessness, morbidity and mortality

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19
Q

Anxiety is escalated by:

Noise of alarms, equipment, personnel
Bright ambient lighting
Excessive stimulation from inadequate pain relief
Frequent ______
Repositioning
Lack of mobility
Uncomfortable __________
Sleep deprivation
Circumstances leading to admission

A

assessments, room temperatures

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20
Q

Pain:

Results from a signal cascade within the neurological network
______: comes from irritation or damage to the nervous system. bones muscles, soft tissue.
_______: Diffuse, poorly localized, often referred. from organs and blood vessels.
Is a ______ mechanism because it stimulates movement away from the thing causing harm

A

Somatic pain, Visceral pain, protective

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21
Q

Negative effects of pain & anxiety

Associated with a 10 year increase in mortality rate after PCI
__________ secondary to pain and anxiety is stressful because the rapid breathing increases patient effort

A

Hyperventilation

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22
Q

Negative effects of pain & anxiety:

Causes feelings of breathlessness that lead to __________ with the ventilator
_________________ can be a result of dyssynchrony

A

dyssynchrony, Alveolar damage

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23
Q

Physiological responses to pain and anxiety:

______
Cool extremities
Diaphoresis
__________________
Increased cardiac output
Increased______ production
Pupillary ______ (mydriasis)
Nausea
Pallor and flushing
Sleep disturbance
Tachycardia
Tachypnea
_______

A

Constipation, Hypertension, glucose, dilation, Urinary Retention

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24
Q

2 years post ICU stay study:

59% of patients still experienced general anxiety, depression, and PTSD
35% had PTSD symptoms during follow up
50 % had taken ___________ drugs
40 % required psychiatric treatment since hospital discharge

A

psychiatric

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25
Agitation risk factors: Extreme anxiety Moderate to severe pain Delirium Mechanical ventilation Smoking habits Fun fact: Agitation increases days spent on _____
ventilator
26
for nurses : avoid ______ when possible. counseling can be good for nurses, pet therapy can be good, art therapy can also be helpful,
drugs and alcohol
27
Results of delirium: Sleep disturbances Abnormal psychomotor activity Emotional disturbances If untreated, is a predictor of negative clinical outcomes in critically ill patients Increased _____ , ______, ______ Long-term cognitive impairment consistent with _________
mortality Increased length of stay Increased cost of care dementia-like state
28
American College of Critical Care Medicine & Society of Critical Care Medicine Comprehensive Guidelines: Evidence based practice Patient centered protocols Treat ____ Treat ______ Consider Sedation Focus on delirium, immobility and sleep disruption in critically ill patients Recommends: 1. Validated monitoring instruments 2. Nonpharmacological AND pharmacological interventions 3. Coordinating care around the patient’s goals
Pain, Agitation,
29
What does the ABCDEF bundle mean?
Awakening and Breathing Coordination Delirium monitoring and management Early exercise and mobility (rehabilitation) Family Engagement AND SLEEP
30
What does the ABCDEF bundle result in?
Less time on mechanical ventilation Less delirium Early mobilization Decreased length of stay in the critical care unit and the hospital
31
Pain assessment: Thorough assessment Ongoing assessment Reassessment Documentation of interventions and responses Involves collecting the patient’s report and behavioral markers Should identify and treat possible causes of anxiety too such as _______________________________________________, pain and withdrawal from drugs.
hypoxemia, hypoglycemia, hypotension
32
What is PQRST ?
provocation, quality, radiation, severity, and timing
33
What scale is used on patients who cannot communicate in the ICU?
Critical Care Pain Observation Tool (CPOT)
34
What is the max score on the CPOT?
8
35
What scale do we used for sedated patients?
CPOT
36
Goal: Maintain ______ effective sedation to achieve ______ duration of mechanical ventilation
lightest, shorter
37
1. accumulation of medication 2. increased hospital stay 3. pneumonia 4. delayed ventilator weaning 5. immobility
consequences of too much sedation
38
1. Agitation 2. Inappropriate use of paralytics 3. Increased metabolic demand 4. Increased risk of myocardial ischemia
consequences of not enough sedation
39
check _____ to see how well gut is absorbing food.
residuals
40
Rass scale is how we determine if our patients are ______ appropriately.
sedated
41
1. 10 point scale ranging from ______ (4+) to _____________ (-5) 2. Patient is assessed for _____ seconds 3. Light sedation: _________ 4. Light sedation is the ____________
combative unarousable 30-60 (-2) up to (+1) ideal range
42
_______ tells us if we need to turn sedation up or down.
rass
43
What is another scale beside the CPOT and RASS, what is its scale?
Sedation agitation scale. 1 (unrousable) to 7 (dangerous agitation)
44
Records spontaneous brain activity that comes from cells on the surface of the brain Converts EEG signal into a numeric score 0-100 (100 = fully awake)
BIS monitor
45
________________ noninvasive, objective analysis on the level of the patient’s wakefulness
BIS provides
46
BIS has strong correlation with ?
RASS score
47
BIS BISPECTRAL INDEX SCORE ____= Full consciousness _____=Deep sedation ___= Complete EEG supression
90 40-60 0
48
Measurement of pupil size and reactivity to light Uses an infrared camera to noninvasively monitor pupil diameter changes Allows for assessment of ______
opiod administration. Pupil dilation reflex (pupillometry)
49
______ = significant central opiod effect, which indicates that the patient would be better treated with: Regional block Ketamine Other non-opiod therapy
Pain + LOW PDR
50
Ketamine: Anesthetic Interrupts association pathways of the brain selectively Provides sensory blockade Can be used for _____ or _____
PAIN, RSI
51
What is ketamine dose for pain?
IV bolus 0.2-0.3 mg/kg with mas of .35 mg/kg
52
What is the RSI dose for ketamine?
2 mg/kg
53
What is a common side effect of ketamine?
nightmares
54
What does the RSI dose of ketamine do?
inhibit breathing
55
UNDERSTAND THAT THIS MAY MAKE YOUR PATIENT GOOFY, HALLUCINATION, DISORIENTED, INCREASES BP AND ICP
ketamine
56
Ketamine: NMDA side effects
Can cause emergence reaction an acute confusion state during recovery from anesthesia; patients with ED may present with disorientation, hallucination, restlessness, and purposeless hyperactive physical behavior Hypertension Respiratory Depression Apnea Nausea and vomiting Anaphylaxis Can increase ICP
57
not appropriate for patients with already high ICP
ketamine
58
Ketamine: Nurse Job
Monitor BP, HR, respiratory status Protect the airway (from vomiting most likely) Use very cautiously in patients with head injury as this can increase ICP Provide safety in the event of unpleasant hallucinations, confusion, excitement Educate patient and family before administration PROVIDE SAFETY
59
one person will monitor the patient and they will be assigned this job this is all they do, will just watch the monitor.
When RSI dose of ketamine is given
60
______ are the only ones who can do moderate sedation
physicians
61
provide safety: ABC, bed rails up, intervening for ABC issue, main goal is to keep patient safe.
honestly everything, but for ketamine
62
always use the ___ dose vial
smaller
63
Changing or fluctuating mental status Inattention Disorganized thinking Altered levels of consciousness Elderly patients more at risk
delirium
64
45-87% of patients who are critically ill experience this If untreated may result in longer ventilation and stay
delirium
65
_______________: agitated, combative, disoriented, at elevated risk for injury because of altered thought processes and behaviors. May experience hallucinations, delusions, paranoia
Hyperactive Delirium
66
_______________: “quiet __________” that often goes undiagnosed theyre super confused and no one really knows bc theyre quite
Hypoactive Delirium, delirium
67
___________: have features of both delirium
Mixed Delirium
68
Non-pharmacological therapy for pain, anxiety, and delirium
Orient with calendars and clocks Engage the family Role model to the family reassurance Role model avoiding arguing with confused patients Teach family how to do passive ROM Teach family how to help with hygiene Bring in pictures and keepsakes from home to improve environment Let the patient face the window Conceal equipment
69
what are alternative therapies ?
guided imagery, music therapy, essential oils and aromatherapy, animal therapy,
70
Improved pulmonary function Earlier ambulation Earlier mobilization Decreased stress response Lower catecholamine concentration (pressors) Lower oxygen consumption Improved outcomes
appropriate pain management results
71
__________: Fastest onset. Shortest duration doesn’t typically lower bp really fast. don’t slam –-__________, give over ______ minutes
FENTANYL. chest wall rigidity, 2-5
72
_________: Longer duration. May cause hypotension or prolonged sedation in patients with renal insufficiency decreased O2 demand increases vasodilation give over 2-5 minutes if given too fast –__________
MORPHINE, causes vomiting lowers BP
73
_______: Prepare to apply o2 have a nasal canula nearby works really well, but it wears off really quickly
HYDROMORPHONE
74
if youre giving IV push of opiods or benzos –give over _________
2-5 minutes
75
What is a typical IV dose of fent?
50-100 mcg q1 -2 hours IV is a normal dose
76
what are side effects of fent?
Bradycardia, Hypotension, CHEST WALL RIGIDITY, muscle rigidity, constipation, itching
77
Is more pressure-protective than other opiods
fent
78
occasionally used for sedation, but mostly for pain, what happens if you give it too fast?
chest wall rigidity
79
How fast should you give morphine?
Give SLOWLY over 4-5 min
80
what can morphine's side effects be?
resp depresion n/v
81
what are nursing interventions for morphine?
Apply o2 PRN Monitor vitals and intervene PRN Use lower doses in older adults
82
what is an appropriate dose of morphine for an adult?
2-10 mg
83
What is the dose for hydromorphone?
0.2-1 mg IV q2-3 hours for severe pain
84
What are the side effects of hydromorphone?
Respiratory depression Hypotension
85
What are nursing care interventions for hydromorphone?
Prepare to give o2 -Give SLOWLY (2-5 minutes) -Note that the potency of hydromorphone to morphine is 7:1 -Avoid giving to opiod naïve patients Antidote: Naloxone/Narcan
86
Patient controls when med is given Special infusion pump Patient pushes a button for a prescribed bolus of pain medication Safe and effective pain management
PCA pump
87
What is the antidote for benzodiazepines?
flumazenil
88
What scales do you use to assess sedative benzos?
SAS or RASS
89
What are benzos used for?
sedation, anxiety, seizures
90
what is the dose for midazolam?
0.01-0.05 mg/kg over 2-3 min IVP 0.02-0.1 mg/kg/hr continuous infusion
91
What are the side effects of benzos?
CNS depression hypotension, resp depression paradoxical agitation
92
What can happen if we give them flumazenil?
seizures
93
propofol is known as ?
jackson juice, milk of amnesia, or diprivan
94
propofol tubing has to be changed ?
q 12 hrs bc of bacteria
95
what do you need to monitor with propofol?
triglyceride levels
96
propofol: Rapid increases in administration rate can cause ______________________! ***
cardiorespiratory depression. only increase doses every 3-5 minutes bc of this
97
Can NOT be given IVP by a nurse in OK but it CAN be managed on a pump.
propofol
98
what do you need to monitor for with propofol?
CNS depression, respiratory depression, hypotension, fever, sepsis, hyperlipidemia
99
propofol: Initial infusion rate _____________ for 5 min
5mcg/kg/min
100
Loss of sensation, consciousness and reflexes -Used for MAJOR surgery requiring complete muscle relaxation
general anesthesia
101
Loss of sensation WITHOUT loss of consciousness -used for a particular part of the body
local anesthesia
102
during moderate sedation you will never give a _______
paralytic
103
ALWAYS GIVE ___________ BEFORE ____________ WITH THE EXCEPTION OF IF THEY ARE COMBATIVE
SEDATIVE, PARALYTIC
104
anesthesia: ______ is the #1 priority in all situations Titrate meds CAREFULLY and SLOWLY ______________ can deteriorate quickly with sedation and should be monitored closely for cardiac complications With the use of anesthesia, ALWAYS inquire about ________________. damages CNS
Airway patency, Elderly individuals, malignant hyperthermia
105
what is the reversal for malignant hyperthermia?
dantrolene
106
THIS IS A LIFE THREATENING EMERGENCY INHERITED MUSCLE DISORDER requiring screening questions
malignant hyperthermia
107
treatment for malignant hyperthermia
STOP SURGERY Give Dantrolene (this is a muscle relaxer) What is the dose and how fast is it given? (look this up) 100 % o2 Get ABGs Infuse ICED saline Cooling blankets Indwelling temperature sensing foley catheter
108
dantrolene: What is the dose and how fast is it given?
at least 1 mg/kg. up to 10 mg. fast,
109
anesthesia that does not result in loss of consciousness
moderate sedation
110
Client can *respond to verbal stimuli *retains protective reflexes (gag reflex) *is easily arousable *maintains own airway
moderate sedation
111
Which of the following procedures would be appropriate under moderate sedation? Cholecystectomy Breast Augmentation Closed reduction of the wrist Open fracture reduction of the right femur
closed reduction of the wrist
112
(ONLY GIVE MEDICATIONS THAT CAN ___________________ IN THE PRESENCE OF A PROVIDER SKILLED AND QUALIFIED IN INTUBATION. NEVER GIVE THIS WITHOUT THIS PERSON IN THE ROOM!)***
REMOVE RESPIRATORY DRIVE
113
What is required during moderate sedation?
Consent prior to medications Continuous monitoring An RN who has no other responsibilities at that time must have the job to solely monitor the patient Crash cart with emergency medications, airway and ventilator equipment, defibrillator, IV supplies (should already have a minimum of one patent IV) 100% o2 source and administration supplies such as airways manual BVM and suction equipment ECG monitor and display, non invasive blood pressure monitor, pulse ox, thermometer, stethoscope, ETCO2***, A PROVIDER CAPABLE OF INTUBATING******** ETco2: Measures the exhaled oxygen with each breath and is an indicator of _____ _________.
114
ETco2: Measures the exhaled oxygen with each breath and is an indicator of _____ _________.
adequate ventilation
115
End tidal Co2 (ETC02) is an indicator of: How well a patient is sedated How well a patient is breathing How much o2 is attached to hemoglobin molecules The rhythm of the heart
how well a patient is breathing
116
you can ventilate them with ______________ so that there is actually a seal. to go ahead and intube, yes you will probably need to remove ___________.
dentures, dentures
117
Never leave the patient. If you are designated to ___________ you may NOT perform any other role. *** Look up moderate sedation on the OK BON website. This is specifically listed. #1 focus is ____________________ status
monitor the patient, cardiac and respiratory
118
anti-emetic: Ondansetron/Zofran -decreases risk of ____________ -Can result in _____________
aspiration, prolonged qt interval (arrhythmia)
119
anti-emetic: Phenergan/Promethazine -decreases risk of ________ -includes sedation -high rate of ____________________
aspiration, necrosis with extravasation.,
120
Metoclopramide/Reglan -decreases the risk of ___________ -enhances _______________ -Fun fact: often will make patient feel ______________________________
aspiration gastric emptying the desire to leave immediately
121
Phenergan/promethazine is given how ?
IM ONLY -Cancause phlebitis and tissue necrosis in the vein
122
___________ -found in your crash cart -used for bradycardia or to decrease the risk of bradycardia during surgery -blocks the muscarinic response to ________________ by decreasing salivation, bowel movement, and GI secretions -Slows motility of the GI tract -Decrease saliva, perspiration, and gastric and pancreatic secretions -Decreases the risk of aspiration
Atropine , acetylcholine,
123
What condition is atropine contraindicated to give with?
glaucoma
124
atropine: Preanesthesia (To Decrease Salivation/Secretions) dose
IM IV Subcut (Adults): 0.4–0.6 mg 30–60 min preop.
125
atropine PALS ACLS use: Bradycardia dose
V (Adults): 0.5–1 mg; may repeat as needed every 5 min, not to exceed a total of 2 mg (every 3–5 min in Advanced Cardiac Life Support guidelines)
126
Toxicity and Overdose: atropine If overdose occurs, ____________ is the antidote.
physostigmine
127
What are s/s of anticholingeric toxidrome?
Altered mental status, mydriasis (blindness), red flush skin, hot dry skin, dry mucous membranes
128
Atropine may cause dry mouth and difficulty voiding. t/f
true
129
Primary use of atropine is: To slow the GI tract To prevent patients from needing to go to the bathroom during moderate sedation To dry sections and keep heart rate above 60 To alleviate pain
to dry secretions and keep HR >60
130
Are neuromuscular blocking agesnts used in moderate sedation?
no. you NEVER GIVE NMBA WITHOUT SEDATION
131
__________________: -has a short half-life (less than ______), is either off or on, can cause ______ -avoid use of this in ______ patients. Why?
Succinylcholine 10 min hyperkalemia dialysis
132
HYPERKALEMIA IS A BIG DEAL –HIGH POTASSIUM LEVELS, BRAIN INJURY PATIENTS ARE ALSO NOT GREAT CANDIDATES FOR THIS DRUG,
succinylcholine
133
Rocuronium -has longer half life (about ______) BETTER FOR ____________________________________ TYPICALLY NOT USED FOR THE NORMAL PEOPLE BC IT LASTS ______ MINUTES, IF YOU DON’T GET THE AIRWAY YOU MIGHT HAVE TO BAG THEM FOR ____________.
30 min, DIALYSIS AND BRAIN INJURY PATIENTS, 30, 30 MINUTES
134
Vecuronium: -has a long half life (about an _____) -is often used during _____________ IS MORE LONG TERM, NOT USED for _____ WHEN PATIENTS CODE –___________________________ –THIS IS GIVEN TO PREVENT SHIVERING
hour therapeutic hypothermia RSI THERAPEUTIC HYPOTHERMIA
135
Paralytics are also known as NMBA Paralytics are NOT given during _____________ One nurse must be dedicated to the monitoring of the patient while he or she is undergoing the procedure Common drugs given for moderate sedation include ___________________________________
moderate sedation Ketamine, Diprivan/propofol and versed/midazolam
136
paralytics are aka NMBA: _____________________________
succintylcholine, rocuronium, vecuronium
137
versed –decreases ____, -it will affect your _______________ almost every time
bp, blood pressure
138
etomidate is __________ and _____________________succinylcholine for RSI
~20 mg, 100 mg