Sedation Flashcards

1
Q

Mechanism of midazolam

A

Increases activity of GABA (an inhibitory neurotransmitter) in the CNS resulting in hyper polarization of neuronal cells that take longer to depolarize

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2
Q

Mechanism of ketamine

A

Non competitive NMDA receptor antagonist that blocks glutamate reducing polysynaptic spinal reflexes.

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