Section test 1 Flashcards

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1
Q

Autoimmune disease

A

Body thinks self is foreign.

Antigen=what the abnormal antibody being produced is attacking (what body thinks is foreign)

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2
Q

Substrate

A

Substance that is acted upon by another compound, typically an enzyme.

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3
Q

Parts of an Inducible operon

Negative vs Positive control

A

Inducer, Repressor, Operator, Promoter, Structural genes, co-repressor, activator protein

Positive=activator protein
Negative=repressor

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4
Q

Parts of an Repressible operon

Attenuation

A

Regulatory molecule

Loops

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5
Q

Competitive inhibitor

A

Mimics another substance which causes a reaction instead of inhibiting it

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6
Q

Missense mutation

A

Mutation causes change in one codon

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7
Q

Renin-Angiotensin-Aldosterone system

A

In response to low BP.

Angiotensinogen secreted by liver.
Renin secreted by kidney and converts angiotensiogen to Ang I.
ACE converts Ang I to Ang II
Ang II=increase symp., tubular reabsorption, increase ADH and aldosterone.

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8
Q

Altitude and its effects on PO2 and PCO2

A

Increased elevation=decrease in PO2 and PCO2

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9
Q

Germ Layers

A

Mesoderm
Ectoderm
Endoderm

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10
Q

Sympathetic stimulation

A
Eye=dilates pupil
Heart=increase HR and contractile force
Lungs=dilate bronchioles (via adrenaline)
Bld vessels=dilate skeletal; constrict in GI
Sweat Glands=increase sweat secretion
Digestive=decrease peristalsis
Kidney=increase renin
Penis=flaccid
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11
Q

Cerebellum

A

Located in Hindbrain
Responsible for muscular coordination
Ex. Hand-eye coordination, posture, balance

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12
Q

Hindbrain

A

Sensory and motor control

Contains cerebellum, pons and medulla

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13
Q

Pons

A

Hindbrain.
Sleep, respiration, swallowing, bladder control, hearing, equilibrium, taste, eye movement, facial expressions, facial sensation.

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14
Q

Medulla

A

Hindbrain.

Breathing, heart rate, blood pressure (involuntary)

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15
Q

Cerebrum

A

Located in forebrain.
Right and left hemispheres.
4 Lobes=frontal, parietal, temporal, occipital

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16
Q

Parietal lobe

A

Cerebrum (forebrain)

Sensation

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17
Q

Temporal Lobe

A

Cerebrum (forebrain)

Hearing, memory, language, speech

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18
Q

Occipital lobe

A

cerebrum (forebrain)

Vision

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19
Q

Frontal Lobe

A

Cerebrum (forebrain)

personality, speech, motor control

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20
Q

Aldosterone

A

Produced by adrenal cortex.
Steroid.
Increase ion and water reabsorption.

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21
Q

ADH/vasopressin

A

Released by posterior pituitary.

Increase water reabsorption (& constrict bld vessels).

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22
Q

Isoenzymes

A

Enzymes that differ in structure but have the same function

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23
Q

Thyrotropin

A

Released from hypothalamus.

Stimulates thyroid gland to release thyroxine.

24
Q

Thyroxine (T4)

A

Secreted by thyroid.

Metabolism regulation.

25
Q

Oxytocin

A

Made by hypothalamus and released by anterior pituitary

Uterine contraction and contraction for milk flow

26
Q

Calcitonin

A

Bone formation and lowers bld calcium

Produced by thyroid

27
Q

Lipid Digestion

A

Mouth=lipases

Gallbladder=stores and releases bile to intestine.

28
Q

Protein Digestion

A

By small intestine and stomach.

Stomach=HCl and pepsin

Small intestine=in duodenum; enzymes from pancreas trypsin and chymotrypsin

29
Q

Carbohydrate digestion

A

Mouth=enzyme amylase
Small intestine=pancreatic enzyme amylase
Large intestine=takes care of anything left

30
Q

Nucleic acid digestion

A

In small intestine by pancreatic enzymes

31
Q

Acetylcholinesterase

A

Enzymes that breaks down ACh.

32
Q

Acetylcholine

A

Causes depolarization of postsynaptic neurons

33
Q

Muscle contraction

A

Stimulus causes release of Ca2+ in sarcoplasmic reticulum of muscle fibers.
Ca2+ binds to troponin to move tropomyosin and expose myosin binding sites on actin.
ATP hydrolyzed (removed) so myosin has affinity for actin.

34
Q

Nonsense mutation

A

Results in premature stop codon

35
Q

Frameshift mutation

A

Deletion of non-three multiples of nucleotides

36
Q

Autosomal dominant disease

A

Only need one bad copy of gene to get disease.

Ex. AA or Aa

37
Q

Erythropoietin

A

Hormone released by kidneys.

Increases RBC formation.

38
Q

Refractory periods of action potentials

A

Absolute refractory period=closing of Na+ channels.
Another stimulus would cause no action potential

Relative refractory period=when K+ channels open
Strength of stimulus determines action potential size

39
Q

Hormones that control bld glucose

A

Insulin=secreted by pancreas, decreases bld glucose

Glucagon=secreted by pancreas, increases bld glucose

Catecholamines (epi and norepi)=adrenal glands, epi decreases and norepi increases (net increase)

Growth hormone=hypothalamus/ant. pit., increase bld glucose

Corticosteroids=adrenal glands, increase bld glucose

40
Q

Cerebral cortex

A

logical thought, emotions, memory

41
Q

Peripheral Nervous System

A

Controls mvmt of skeletal muscles, respiration

42
Q

Somatic mutation

A

Occurs during mitosis and not caused by parent

43
Q

Germline mutation

A

Meiotic mutation that parent passes to child

44
Q

Schwan Cells

A

Cause myelination of nerve cells.

Unmyelinated portions of nerve called node of Ranvier.

45
Q

RAS protein

A

Causes cell proliferation

46
Q

Gap junctions

A

Intracellular connections that allow molecules to flow freely b/w cells (diffusion)

47
Q

Pepsin

A

Secreted by chief cells of stomach.

Degrades proteins in stomach.

48
Q

Trypsin

A

Secreted by pancreas into duodenum of small intestine.

Degrades proteins.

49
Q

Amylase

A

Secreted by pancreas into duodenum of small intestine.

Degrades carbohydrates

50
Q

Lipase

A

Secreted by pancreas into duodenum of small intestine.

Degrades lipids

51
Q

Cortisol

A

Produced by adrenal cortex (stimulated by ACTH)
Steroid
Maintains homeostasis related to stress (metabolism)

52
Q

ACTH

A

Secreted by hypothalamus (anterior pituitary)

Maintain cortisol levels

53
Q

Adrenal Medulla

A

Sympathetic activity
Secreted norepi and epi.
Epi=acts on adrenergic receptors
Norepi=used largely for hypotension

54
Q

Epiphyseal plates

A

Cartilage cells separate diaphysis (shaft) and dilated ends of long bones.
Found in children and teens.
Responsible for bone growth.

55
Q

Bone types

A

Long bones: shaped like a rod. eg. arm, leg, finger bones.

Short bones: shaped like a cube. eg. wrist, ankle bones.

Flat bones: bones that are flat. eg. sternum, shoulder blades, ribs, skull.

Irregular bones: complicated shapes. eg. vertebrae, hip.

56
Q

Somatostatin

A

Secreted by stomach, intestine and pancreas.
Decreases gastric emptying (less smooth muscle contractions). Decreases insulin and glucagon.

Secreted by hypothalamus.
Reduces GH, TSH, prolactin and adenylyl cyclase.