Section 7: RBC Morphology Flashcards by MC GC

Q

smaller rbcs = Hbg production issue

A

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Q

BIG RBCs = few mitotic division

A

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Q

Perfect sized w/ nice central pallor = evolution baby

A

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Q

Empty looking RBCs = Lacking normal amounts of Hbg

A

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Q

Lavender colored larger RBCs = Left shift => young blood

A

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Q

Egg like/ cylindrical w/ rounded ends = horizontal Spec-Ank protein defect

A

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Q

different shaped cells = Multiple reasons - Spec-Ank protein defect, macrophage bites

A

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Q

Target like cells = Increase in membrane lipid

A

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Q

Guajillo chilies cells w/ point ends = Abnormal Hgb S

A

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Q

Crystal cells (Hgb CC) — Tic-tac red ufo & typical ufo with bubble like light on the bottom = Abnormal Hgb CC

Crystals (Hgb SC) — Birdie shaped cells or end piece of banana

A

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Q

Hgb pushed to one side w/ clear “flap” area & see dense red color on one side of cell and light pallor on the other side = NOT diagnostic

A

En

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Q

Evenly disbursed round goose bumps around the RBC = Change in tonicity of intravascular fluid

A

burr

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Q

RBC w/ long, irregular, spiny/spiky uneven projections =

A

Acanthocytes

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Q

Four different RBC fragments. RBC w/ a bite take out, blister like bubble w/in RBC, helmet shaped RBC, and a triangular shaped RBC.

A

Schistocytes: bite cells, blister cells, Helmet/ horn cells triangle fragments.

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Q

Tear drop shaped RBC = extra-medullary-hematopoiesis. Exact mechanism unknown.

A

Tear drop

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Q

Dark - no pallor, small & round RBC = loss of cell membrane

A

Spherocytes

Q

Coin slot or mouth shaped pallor RBCs = NA+/P+ pump defect

A

Stomatocytes

Q

Clusters/clumps of RBCs = Cold Ab IgM or just clotted

A

Agglutination

Q

Coin-like stacking of the RBCs = Increased plasma proteins act like a positive charge allowing the negative charged RBCs to stack on each other

A

Rouleaux

Q

What RBC abnormality do you see here?

A

Howell-Jolly bodies (inclusions)

Q

Lots of fine to course blue dots evenly dispersed throughout cytoplasm = remanent RNA / wall licking => lead poisoning

A

Basophilic stippling (can see on Wright’s stain)

Q

RBCs w/ small, irregular, blue granules clustered at cell periphery. They look like stain ppt so be careful! = They’re granules of iron that can’t get into Hbg due to bad utilization or excess

Confirm with Prussian blue stain

A

Pappenheimer bodies

Q

RBC w/ thin ring like formation = remnant cell membrane

A

Cabot ring

Q

ONLY visible on SVS. Big dot(s) in RBC (not a lot though) = Precipitated & denatured Hgb due to O2 injury

A

Heinz bodies

Many kind of parasites 1. Spirochetes - look for spirals outside of RBC = infected ticks 2. Malaria - look for 1-2 faint ring formations w/ RBC = infected mosquitos 3. Babesia - 2-3 hole-like appearances w/ RBC = infected ticks 4. Typanosomes = 3 sub types -Wucheria Bancrofti (WB) = contaminated food -Typanosoma Cruzi (TC) = contaminated food -Loa Loa (LL) = contaminated food

Different sized RBC = multiple factors like Hgb production issues & few mitotic division