Section 3 - Unit 7: Mass Transport Flashcards
Explain how oxygen is loaded, transported and unloaded in the blood (6 marks)
- Haemoglobin carries oxygen
- Uptake in lungs;
- At high p.O2;
- Releases to respiring cells
- At low p.O2;
- Unloading linked to higher carbon dioxide concentration
Describe the path by which oxygen goes from an alveolus to the blood (2 marks)
- Through alveolar epithelium
- Through capillary epithelium
Describe how ventilation helps to maintain a difference in oxygen concentration in the lungs (2 marks)
- Brings in air containing a higher oxygen concentration
- Removes air with a lower oxygen concentration
Suggest why blood returning to the heart from the lungs contains some carbon dioxide (2 marks)
- Concentrations reach equilibrium
- Diffusion occurs when there is a concentration gradient
State two ways in which blood plasma is different from tissue fluid (2 marks)
- Larger proteins
- More glucose
Explain how the left ventricle causes the blood to be at high pressure (1 mark)
- It contracts
Explain why blood pressure decreases along the length of the capillary (2 marks)
- Loss of fluid/volume
- Friction/resistance of capillary wall
Explain how the shape of a red blood cell allows it to take up a large amount of oxygen in a short time (2 marks)
- Large surface area to volume ratio
- For diffusion
Explain why producing a much higher ventricular blood pressure than normal can cause tissue fluid to build up outside the blood capillaries (2 marks)
- More fluid forced out of blood/capillary
- Less fluid returns back to the capillary (due to high blood pressure)
Suggest how widening of blood vessels can reduce ventricular blood pressure (2 marks)
- Larger lumen
- This reduces blood pressure (less friction)
State which blood vessel carries oxygenated blood away from the heart (1 mark)
- Aorta
State which blood vessel carries deoxygenated blood to the heart (1 mark)
- Vena Cava
Explain how the highest blood pressure is produced in the left ventricle (1 mark)
- Strongest/stronger contractions
Suggest why having a hole between the right and the left ventricles means that sufficient oxygen doesn’t reach the rest of the body tissues (2 marks)
- Oxygenated and deoxygenated blood mix
- So a lower volume of oxygenated blood leaves left ventricle
Describe the role of haemoglobin in supplying oxygen to the tissues of the body (2 marks)
- Oxyhaemoglobin formed/haemoglobin is loaded/associates with oxygen in area of higher ppO2
- Oxygen is unloaded in an area of lower ppO2 (in tissues)
Explain how tissue fluid is formed (2 marks)
- Outward pressure of 3.2 kPa
- Forces small molecules out of capillary
Explain how high blood pressure leads to an accumulation of tissue fluid (3 marks)
- High blood pressure = high hydrostatic pressure
- This increases outward pressure from (arterial) end of capillary
- So more tissue fluid formed/less tissue fluid is reabsorbed
Explain why the water potential of the blood plasma is more negative at the venule end of the capillary than at the arteriole end of the capillary (3 marks)
- Water has left the capillary
- Proteins in blood are too large to leave capillary
- Increasing concentration of blood proteins (and thus water potential)
Explain the function of the coronary arteries (2 marks)
- Carries oxygen/glucose
- To heart muscle/tissues/cells
Explain why although the speed of blood flow in an arteriole is greater than the speed of blood flow in a capillary, blood does not accumulate in the arterioles (1 mark)
- Area of capillaries is much larger than arterioles
Other than causing slow blood flow, explain one advantage of capillaries being narrow (1 mark)
- Fast diffusion
What factor limits the minimum internal diameter of the lumen of a capillary (1 mark)
- Diameter of blood cell
Explain why the volume of blood leaving the capillary network into the veins is less than the volume of blood entering from the arteries (1 mark)
- Fluid in tissue fluid
Explain the importance of maintaining a constant blood pH (3 marks)
- Haemoglobin protein in blood is sensitive to pH
- Resultant change of tertiary structure
- So less oxygen binds to haemoglobin
Explain the advantage of the oxygen dissociation curve for haemoglobin shifting to the right during vigorous exercise (3 marks)
- Lower affinity for oxygen
- Faster unloading to muscles/tissues/cells
- For rapid respiration
Explain how the heart muscle and the heart valves maintain a one-way flow of blood from the left atrium to the aorta (5 marks)
- Atrium has higher pressure than ventricle causing atrioventricular valves to open
- Ventricle has higher pressure than atrium causing atrioventricular valves to close
- Ventricle has higher pressure than aorta causing semilunar valve to open
- Higher pressure in aorta than ventricle causing semilunar valve to close
- Contraction causes increase in pressure
The oxygen dissociation curve of the fetus is to the left of that for its mother - explain the advantage of this for the fetus (2 marks)
- Higher affinity/partial pressure
- So oxygen moves from mother to fetus
Name the blood vessel to which an artificial heart is connected (1 mark)
- Aorta
Suggest why the artificial heart mainly helps the left ventricle and not the right ventricle (2 marks)
- Left ventricle pumps to whole body
- So it does most work/produces a greater pressure
Suggest why the pulse felt can be used to measure heart rate (2 marks)
- The pulse is caused by pressure
- From one contraction
Explain why an arteriole is described as an organ (1 mark)
- Made up of more than one tissue
Explain how muscle fibres in an arteriole reduce blood flow to capillaries (2 marks)
- The muscle contracts
- And narrows the capillaries
Give the advantage of blood flow in capillaries being slow (1 mark)
- More time for exchange of substances