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Kaplan Pharm > Section 2: Autonomics > Flashcards

Section 2: Autonomics Flashcards

1
Q

Hemicholinium

A

Class: ACh reuptake inhibitor

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2
Q

Botulinum toxin

A

Class: ACh release inhibitor
Mech: inhibits SNARE proteins

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3
Q

Bethanachol

A

Class: Direct-acting cholimimetic
Use: Ileus, urinary retention

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4
Q

Methacholine

A

Class: direct-acting cholimimetic
Use: Dx bronchial hyperreactivity

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5
Q

Pilocarpine

A

Class: Direct-acting cholimimetic
Use: Glaucoma (topical), xerostomia

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6
Q

Edrophonium

A

Class: AChEI
Use: Dx myasthenia gravis

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7
Q

Physostigmine

A

Class: AChEI
Use: Glaucoma, antidote for atropine OD
Note: Tertiary amine, enters CNS

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8
Q

Neostigmine

A

Class: AChEI
Use: Ileus, urinary retention, myasthenia gravis, reversal of non-depolarizing NMJ blockers

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9
Q

Pyridostigmine

A

Class: AChEI
Use: Ileus, urinary retention, myasthenia gravis, reversal of non-depolarizing NMJ blockers

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10
Q

Donepezil

A

Class: AChEI
Use: Alzheimer disease
Note: Lipid soluble, enters CNS

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11
Q

Organophosphates

A

Class: AChEI
Use: Glaucoma (echothiophate)
Note: Lipid soluble, irreversible inhibitors

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12
Q

Atropine

A

Class: M receptor antagonists
Use: Antispasmodic, antisecretory, AChE OD, antidiarrheal, ophthalmology

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13
Q

Tropicamide

A

Class: M receptor antagonists
Use: Ophthalmology

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14
Q

Ipratropium, tiotropium

A

Class: M receptor antagonists
Use: Asthma & COPD (inhaled)

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15
Q

Scopolamine

A

Class: M receptor antagonists
Use: Motion sickness
S/E: Sedation, short-term memory block

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16
Q

Benztropine

A

Class: M receptor antagonists
Use: Parkinsonism, acute extrapyramidal symptoms induced by antipsychotics

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17
Q

Trihexphenidyl

A

Class: M receptor antagonists
Use: Parkinsonism, acute extrapyramidal symptoms induced by antipsychotics

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18
Q

Hexamethonium

A

Class: Ganglion blocker

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19
Q

Mecamylamine

A

Class: Ganglion blocker

20
Q

Phenylephrine

A

Class: α1 agonist
Use: Nasal decongestant, ophthalmology (mydriasis w/o cycloplegia)

21
Q

Clonidine, methyldopa

A

Class: α2 agonist
Use: HTN

22
Q

Isoproterenol

A

Class: Nonselective β agonist
Use: Bronchospasm, heart block, bradyarrhythmias
S/E: Flushing, angina, arrhythmias

23
Q

Dobutamine

A

Class: β1 agonist
Use: CHF
Note: β1 > β2

24
Q

Salmeterol

Albuterol

A

Class: β2 agonist
Use: Asthma

25
Q

Terbuatline

A

Class: β2 agonist
Use: Asthma, premature labor

26
Q

Norepinephrine

A

Class: α1, α2, β1 agonist
Use: Cardiac arrest, adjunct to local anesthetic, hypotension

27
Q

Epinephrine

A

Class: Mixed adrenergic agonist (hits all 4 receptors)
Use: Cardiac arrest, adjunct to local anesthetic, hypotension, anaphylaxis, asthma
Low dose looks like isoproterenol, high dose looks like NE

28
Q

Tyramine

A

Class: Indirect adrenergic agonist; releaser
Note: In red wine, fancy cheezes and meats

29
Q

Amphetamines

A

Class: Indirect adrenergic agonist; releaser
Use: Narcolepsy, ADHD (methylphenidate)

30
Q

Ephedrine

A

Class: Indirect adrenergic agonist; releaser
Use: Cold medication

31
Q

Cocaine

A

Class: Indirect adrenergic agonist; reuptake inhibitor

32
Q

TCAs

A

Class: Indirect adrenergic agonist; reuptake inhibitor

33
Q

Phentolamine

A

Class: Nonselective α antagonist
Use: HTN during surgery, Dx pheochromocytoma

34
Q

Phenoxybenzamine

A

Class: Nonselective α antagonist
Use: Pheochromocytoma

35
Q

-zosyns

A

Class: α1 antagonist
Use: BPH
Examples: Prazosin, Doxazosin, Terazosin, Tamulosin

36
Q

Mirtazapine

A

Class: α2 antagonist
Use: Depression

37
Q

Pindolol

A

Class: β antagonist
Use: Angina, HTN, post-MI

38
Q

Propranolol

A

Class: β antagonist
Use: Angina, HTN, post-MI, antiarrhythmic, migraine, thyrotoxicosis, performance anxiety, essential tremor

39
Q

Timolol

A

Class: β antagonist
Use: Angina, HTN, post-MI, glaucoma

40
Q

Atenolol

A

Class: β antagonist
Use: Angina, HTN, post-MI

41
Q

Metoprolol

A

Class: β antagonist
Use: Angina, HTN, post-MI, glaucoma
Note: Same as atenolol

42
Q

Carvedilol

A

Class: α1 and β antagonist
Use: Angina, HTN, post-MI, CHF

43
Q

Labetalol

A

Class: α1 and β antagonist
Use: Angina, HTN, post-MI, HTN emergency

44
Q

Sotalol

A

Class: β & K+ channel antagonist

45
Q

Acebutolol

A

Class: β1 antagonist
Use: Angina, HTN, post-MI, antiarrhythmic

Kaplan Pharm (10 decks)

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