Section 14 - Overfills Flashcards

1
Q

What is the shelf life of an IV product?

A

The length of time it would normally take before the contents are reduced to the nominal or labeled volume

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2
Q

How is the rate of loss for IV products determined?

A

By the permeability of the bag, fluid volume to surface ratio, and storage conditions

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3
Q

The overfill volume may allow for ___ of IV lines

A

Priming

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4
Q

What should be done in cases where a significant portion of the dose will remain in the IV tubing?

A

Instructions regarding flushing the line should be provided

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5
Q

What is involved in preparation of a compounded medication infusion?

A

Diluting the drug w/ a diluent and transferring the prescribed amount of drug into a final dosage container

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6
Q

What does the preparation method used affect?

A

Total volume and concentration of the final product

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7
Q

What are the possible practitioner-based methods?

A

1) Adding to a commercial container (simple admixture)
2) Withdrawal prior to admixture (drug volume)
3) Withdrawal prior to admixture (drug volume and overfill volume)
4) Starting w/ an empty container

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8
Q

What is involved in the method of adding to a commercial container?

A

Medication is added to a manufacturer’s base solution container w/o concern for overfill

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9
Q

When is the simple admixture method typically used?

A
  • For administration of intermittently administered solutions when the entire bag is intended to be infused to a single px over a relatively short time (probably less than 1 hr)
  • Also may be used to prepare medications administered via continuous infusion when the effect of the medication is being continuously montiored
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10
Q

What is involved in the drug volume method?

A
  • Volume of base solution equal to the volume of the medication to be added to the container is withdrawn from the manufacturer’s container, w/o concern about overfill
  • Medication is then added to remaining volume in container
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11
Q

When is the drug volume method typically used?

A

When the volume of medication to be added is large relative to the size of the base solution container

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12
Q

What is involved in the withdrawal prior to admixture method?

A
  • Volume of the base solution equal to the volume of the medication to be added to the container and the estimated volume of overfill is withdrawn from the manufacturer’s container
  • Medication is then added to the remaining volume in the container
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13
Q

When is the drug volume and overfill volume method used?

A

When the volume of medication to be added is large relative to the size of the base solution container

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14
Q

What is involved in the method of starting w/ an empty container?

A
  • Both the measured amount of medication and base solution are added to an empty IV bag or syringe
  • No overfill, so this method may be used when both the total amount of drug in the final container and the concentration of drug need to be accurately known
  • Final container can be labeled w/ a specific drug [ ]
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15
Q

For the first 3 practitioner-based methods, what should the container be labeled w/?

A

Total amount of drug in the container and the total estimated volume

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16
Q

What is done for a manufacturer-based method?

A
  • Manufactured medication is made in large quantities to a specific [ ]
  • Required volume of this solution, including overfill is added to an empty parenteral container
  • Concentration is stated on the label and volume on the label doesn’t include overage
17
Q

What does the ISMP recommend for safe practice?

A
  • Clearly define processes
  • Ensure consistency in the preparation process of continuous infusions
  • For a single dose drug infusion, the entire dose in the container is administered
  • Guide the processes (develop protocols that specify how drug infusions should be prepared)
  • Specificity on labels
18
Q

What should be included on the product label of an infusion in which the dose remaining in the tubing must also be infused to deliver the entire dose?

A

Label should specify that the tubing should be flushed w/ a particular diluent and volume

19
Q

When are overfills required and why?

A

In small volume parenterals in order to ensure that the full content constituting the dose can be withdrawn and administered to the patient