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TB Treatment > Second Line TB Meds > Flashcards

Second Line TB Meds Flashcards

1
Q

Bedaquiline

A

first new drug for TB in 40 yrs

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2
Q

Bedaquiline MOA

A

inhibits mycobacterial ATP synthase

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3
Q

Bedaquiline ADR

A

QT prolongation, increased risk of death, HA, nausea etc

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4
Q

What p450 enzyme is Bedaquiline a substrate for?

A

CYP3A4

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TB Treatment (3 decks)

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