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Vicky's Cards - Exam 1 > Second > Flashcards

Second Flashcards

1
Q

AEDs

A

antiepileptic drugs

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2
Q

gingival hyperplasia is associated with what drug?

A

phenyltoin

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3
Q

Indication for carbamazepine

A

monotherapy for partial seizures with complex symptomatology (psychomotor, temporal lobe), generalized tonic-clonic seizures (gran mal)

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4
Q

Indication for clonazepam

A

absence and myoclonic seizures, seizure clusters

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5
Q

What class of drug is clonazepam?

A

benzodiazepine

only take at night

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6
Q

Indication for ethosuximide

A

absence

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7
Q

What is the DOC for petite mal/absence seizures?

A

ethosuximide

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8
Q

Indication for felbamate

A

monotherapy and adjunctive therapy for partial-onset seizures and tonic-clonic seizures in people over the age of 14

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9
Q

What drug can be used to treat atonic seizures associated with LGS in children aged 2 to 14?

A

felbamate

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10
Q

AE of felbamate

A

aplastic anemia

liver failure

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11
Q

_____________ is only used in pt w/very severe epilepsy d/t adverse effects (Liver failure, aplastic anemia)

A

felbamate

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12
Q

_____________ is used as a add on therapy for partial seizures with or without secondary generalization in patients 12 years of age and older

A

gabapentin

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13
Q

_______________ is intended more for partial seizures

A

gabapentin

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14
Q

What are the AE of gabapentin?

A

unsteadiness
weight gain
fatigue
dizziness

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15
Q

Gabapentin is recommended in use for those ages _____ and older

A

12

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16
Q

Gabapenin is not effective for ___________ seizures

A

primary
absence
myoclonic
primary generalized tonic-clonic

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17
Q

Gabapentin (_________)

A

neurontin

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18
Q

Gabapentin can also be used for the treatment of _________________

A

fibromyalsia

works on gaba receptor, which is inhibitory

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19
Q

dont need to know lacosamide…

A

nope

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20
Q

______________ is a broad spectrum alternative to depakote

A

lamotrigine

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21
Q

What is a benefit of lamictal vs. depakote?

A

less AE

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22
Q

______________ is indicated for simple and complex seizures

A

lamictal

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23
Q

_____________ is used to treat seizures associated with lennox-gastaut syndrome

A

Lamictal

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24
Q

AE of Lamictal

A

dizziness
fatigue
insomnia
SJS –rare

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25
Q

_______________ is an add on therapy for partial-onset seizures

A

levetiracetam

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26
Q

Ages 4, use keppra to treat ____________

A

partial onset seizures

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27
Q

Ages 12, use keppra for__________

A

juvenile myclonic epilepsy

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28
Q

AE of keppra

A

irritability
hostility
depression (1/3 of pt)
rash

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29
Q

______________ is similar to carbamazepine except its not as effective against absence or myoclonic seizures

A

oxacarbazepine

30
Q

AE of oxacarbazepine

A

anaphylaxis
angioedema
hyponatremia
SJS

31
Q

Oxacarbazepine must be taken at least ______ times a day

A

at least 2

32
Q

___________ is an add on therapy for partial and tonic clonic seizures

A

phenobarbital

33
Q

phenobarbital is a good therapy for _____________

A

status epilepticus

34
Q

How do you take phenobarbital?

A

at night, its a barbituate

35
Q

AE of phenobarbital

A 
respiratory OD
sedation 
SJS
liver/blood disorder
dependence 
fetal health
36
Q

Phenobarbital (_______)

37
Q

The indications for oxacarbazepine are the same as _________________

A

carbamazepine

38
Q

______________ is used as monotherapy for partial seizures and primary GTC

39
Q

Phenytoin is safe for what age group?

40
Q

______________ is best for partial onset seizures

41
Q

_____________ is generally not very effective against clonic, myoclonic and atonic seizures and in the lennox-gastaut syndrome

42
Q

Phenytoin is _________________ against lennox-gastaut syndrome

A

not effective

43
Q

Phenytoin _______________ be used for febrile seizures in infants

A

should not

44
Q

AE of phenytoin

A

unsteadiness and moderate cognitive problems, difficult to control levels, bone health, fetal heath, rash
**potential cosmetic (body/face hair growth, skin issues)

45
Q

What is a unique AE of phenytoin?

A

Hair growth in random places

**gingival hyperplasia

46
Q

Phenytoin (____) is used for _______________

A

dilantin

maintenance

47
Q

______________ may control the tonic-clonic component of the lennox-gastaut syndrome

A

phenytoin

–but for the most part it has limited value in this syndrome

48
Q

_______________ is an add on therapy for partial and secondarily generalized seizures ONLY

A

pregabalin

49
Q

_____________ will NOT work in primary generalized seizures like absence, myoclonic or primary generalized tonic-clonic seizures

A

pregabalin

50
Q

What is a pro about pregabalin?

A

no drug interactions, no liver metabolism, no protein binding

51
Q

Pregabalin has similar AE as ___________

A

gabapentin

Weight gain, fatigue, dizziness-nothing seriously concerning

52
Q

Dont need to know primidone

53
Q

Dont need to know rufinamide

54
Q

_____________ can be used as monotherapy or as adjunctive therapy for partial onset seizure in children who are between the ages of 2-16

A

topiramate

55
Q

____________ is an FDA approved as initial monotherapy for pateints 10 years of age and older with partial onset or primary generalized tonic clonic seizures

A

topiramate

56
Q

Dosage for topiramate

A

start at 25 bid and increase by that amount weekly

57
Q

AE of topiramate

A

renal stones, glaucoma, weight loss, metabolic acidosis, behavioral issues-depression, agitation, hostility, psychosis, sulfa allergy**

58
Q

__________ are seen in about 1/3 of those taking topiramate

A

cognitive problems

59
Q

Topiramate is available in ______________

A

tablets and sprinkle capsules

60
Q

_______________ is used as monotherapy and adjuctive therapy for partial onset seizures in adults and children ages 2-16

A

topiramate

61
Q

____________ is used for patients of all ages as monotherapy or adjunctive therapy for simple or complex absence seizures

A

valproic acid (depakote)

62
Q

What kind of seizures can you treat with valproic acid?

A

simple or complex absence seizures

partial seizures

63
Q

AE of valproic acid

A

weight gain, tremor, hair loss, GI upset, blood disorders, hepatic or pancreatic injury, bone health (osteoporosis) fetal health

64
Q

What are the indications for vigabatrin?

A

partial seizures with or without secondary generalization, infantile spasms

65
Q

AE of vigabatrin

A

blindness/retinal toxicity

66
Q

What drug is associated with blindness/retinal toxicity?

A

vigabatrin

67
Q

dont need to know zonisamide

68
Q

What are the indications for acetazolamide?

A

absence seizures, unlocalized seizures, catamenial seizures

69
Q

Acetazolamide is also used for the treatment of _____________

70
Q

What drug is also used to treat glaucoma?

A

acetazolamide

71
Q

AE of acetazolamide

A

tinnitus, numbness, tingling, nausea, vomiting, loss of appetite, rash (sulfa allergy), SJS, blood disorders acidosis

Vicky's Cards - Exam 1 (4 decks)

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