sdf Flashcards
what does PTH do
increase plasma Ca+
decrease plasma phosphate; increase urine phosphate
when is PTH secreted?
- low Ca2+
- low levels of 1,25 vit D
- high phosphoate
if high Ca and phosphate => due to ____
high vit D
low Ca2” and low phosphate
low vit D
hypocalcemia => ______ QT interval
hypocalcemia = prolonged QT inverval
hypercalcemia = ____ QT interval
short
what helps to support a nodule is benign
tender
how to treat hypercalcemia of malignany that causes AMS or changes on EKG
aggressive volume expansion with isotonic saline
what cancers cause humoral hypercalcemia (PTHrP release)
squamous cancers
hypercalcemia of malignancy due to: Vit D
lymphomas or granuloma dz
hypercalcemia of malignancy due to: osteoclastic hypercalcmia (direct release of Ca2+
breast cancer
lung cancer
myeloma
low PTH ddx
- hypercalcemia of malig
- vit D toxicity
- thiazide diuiretics
- immobilization
- granulomatous dz
acute hypercalcemia sx
poluria
dehydration
renal impariment
chronic hypercalcemia sx
stones
bones
psuch issues
tx of hypercalcmia w short QT shyndrome
IV hydration and maybe a loop diuiretic
