Screening in Oral Health Care Flashcards

1
Q

What is primary prevention?

A

preventing initiation of disease
e.g. immunisation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Ww

What is secondary prevention?

A

involves identifying disease early and impeding progression and recurrence
e.g. screening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What

What is tertiaty prevention?

A

involves the reduction of the onset of complications
e.g. rehabilitation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is screening?

A

Screening is a process of identifying apparently healthy people who may be at increased risk of a disease condition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the aim of screening?

A
  • interrup natural history of a disease at is asymptomatic stage when it is treatable and progression can be altered
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What principle provides the basis of screening?

A

a detectable preclinical or latent phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the properties of a screening test?

A
  • cheap
  • easy to use
  • easy to interpret
  • safe
  • acceptable
  • reliable
  • valid
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the components of a valid screening tool?

A
  • sensitivity
  • specificity
  • positive predictive value
  • negative predictive value
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is a discrete result?

A

One that has a yes/no answer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is a continous outcome?

A

outcome/result could be between 1 - 100 (or other numbers)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is important for a screening test with a continuous outcome?

A

a definite cut-off point must be determined

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is sensitivity?

A

this is the ability of a test to identify those with the disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is specificity?

A

this is the ability of a test to identify those without the disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the benefit of a test with high sensitivity ?

A

won’t miss any cases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the benefit of a test with high specificity?

A

won’t put too many people through unnecessary further test and/or treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is a true positive result?

A

where it is predicted someone has the disease and they do

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is a true negative result?

A

where it is predicted someone doesn’t have the disease and they don’t

18
Q

What is the equation to calculate sensitivity?

A

TP/(TP+FN)= N
N is the number of people with the disease who test positive

19
Q

What is the equation to calculate specificity ?

A

TN/(TN+FP) = N
N is the number of people without the disease who test nengative

20
Q

What does the positive predictive value refer to?

A

refers to the probability of having the disease/condition after testing positive

21
Q

What is a negative predictive value?

A

refers to the probability of not having the disease/condition after testing negative

22
Q

What is the equation for positive predictive value?

A

TP/(TP+FP)

23
Q

What is the equation of a negative predictive value?

A

TN/(TN+FN)

24
Q

What are the types of screening programmes?

A
  • mass (population) screening
  • selective screening
  • opportunistic screening
25
What groups are targetted in selective screening programmes?
high risk groups
26
What are the important components of a screening programme?
* test * people to take the test * register to invite participants * infrastructure to invite and re-invite participants * people and infrastructure to read the test * people to record test finding * people and infrastructure to take and read further tests * people and infrastructure to treat * support mechanisms * quality assurance mechanisms
27
What are the advantages of screening programmes?
* improved prognosis for some cases * less radical treatment which cures some early cases * resource savings * reassurance for those with negative test result
28
What are the disadvantages of screening programmes ?
* longer morbidity for cases whose prognosis is unaltered * overtreatment of questionable abnormalities * resource costs * false assurance for those with false negative results * anxiety and sometimes morbidity for those with false positive results * hazard of screening test itself
29
List the screening programme criteria as of 1968
* condition being screened should be an important health problem * natural history of condition should be well understood * should be a detectable early stage * treatment at an early stage should be more beneficial than at a late stage * suitable test devised for early stage * test should be acceptable * intervals for repetition should be determined * adequate health service provision should be made for extra clinical work load resulting from screening * risks, physical and psychological, should be less than benefits * costs should be balanced against the benefits
30
When and who updated the screening criteria?
PHE 2015 | public health england
31
The natural history of oral cancer is very well understood. True or false. Based on your answer, will it meet screening criteria as per PHE 2015 guidelines?
False No, criterion not met
32
What precedes an oral cell carcinoma?
Red or white patches
33
What are the screening criteria according to PHE 2015?
1. condition should be an important health problem judged by severity and frequency. Epidemiology, indicence, prevalence and natural history should be understood including development from latent to declared disease. There should be robust evidence about association betweeing risk of disease marker and serious or treatable disease 2. all cost effective primary prevention interventions should have been implemented as far as practicable 3. if the carriers of a mutation are identified as a result of screening the natural history of people with this status should be understood including psychological implications 4. there should be simple, safe, precise and validated screening test 5. the distribution of test values in the target population should be known and a suitable cut off level defined and agreed 6. the test, from sample collection to delivery of results, should be acceptable to target population 7. there should be an effective intervention for patients identified through screening with evidence that intervention at a pre-symptomatic phase leads to better outcomes for the screened individial compared to usual care 8. there should be agreed evidence based policies covering which individuals should be offered interventions and appropriate interventions to be offered 9. there should be evidence from high quality randomised controlled trials that the screening programme is effecive in reducing morbidity and mortality 10. there should be evidence that the complete screening programme (test, diagostic procedures, treatment/intervention) is clincally, socially and ethically acceptable to health professionals and the public 11. benefit gained by individuals from screening programme should outweigh harms for example overdiagnosis or overtreatment, false positives, false reassurance, uncertain findings and complications 12. the opportunity cost of screening programme (testing, diagnosis, treatment, admin, training and quality assurance) should be economically balanced in relation to expenditure on medical care as a whole- should be value for money 13. clinical management of the condition and patient outcomes should be optimised in all health care providers prior to participation in a screening programme 14. all other options for managing the condition should habe been considered (e.g. improving treatment) to ensure that no more cost effective intervention could be introduced or current interventions increased within resources available 15. there should be a plan for managing and monitoring screening programmes and an agreed set of quality assurance standards 16. adequate staffing and facilities for testing, diagnosis, treatment and programme management should be available prior to commencement of screening programme 17. evidence based information explaining purpose and potential consequences of screening, investigation and preventive intervention or treatment, should be made available to potential participanys to assist them in making an informed choice 18. public pressure for widening eligibility criteria for reducing the screening interval, and for increasing the sensitivity of the testing process should be anticipated. Decisions about these parameters should be scientifically justifiable to the public
34
What primary interventions scheme are in place for oral cancers?
* DPs involved in programes to reduce tobacco and alcohol use * existing public and professional awareness campaigns
35
Generally, oral cancers are not inherited. True or false
True
36
Give examples of possible adjunctive tests for oral cancer screening
* vital rinsing or staining with toluene blue, tolonium chloride * light based detection (vizilife, vizilife plus) * VELscope, orascoptic DK * mouth self examination * blood and saliva analysis
37
Dentists can identify red and white patches with ___ sensitivity and ___ specificity
0.74 sensitivity 0.99 specificity
38
Have guidlines on referrals for oral lesions been developed in the context of screening programmes?
No
39
What is the benefit of surgical management of a small lesion ?
reduces need for radiotherapy and associated morbidity
40
There is currently no research comparing the watch and wait versus active treatment for potentially malignant lesions. Does this met the screening criteria according to PHE 2015?
No
41
Simulation modelling of oral cancer screenings in the UK do not suggest cost effectiveness. True or false
False they do suggest cost effectiveness
42
Oral cancer screening lacks knowledge in which ares?
* which lesions become cancerous * a reliable test suitable for UK primary dental care