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Cervical Cancer Screening > Screening and Vaccination Cervical CA > Flashcards

Screening and Vaccination Cervical CA Flashcards

1
Q

What are the tests done in Cervical Cancer Screening?

A

CO-TESTS

HPV DNA Test
Reflex LBC (liquid based cytology)

Colposcopic biopsy

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2
Q

Which HPV genotypes cause cancer?

A

16 and 18

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3
Q

When do you start screening and interval of Cervical Cancer?

A

From 25yrs of age
Every 5 yrs

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4
Q

What tests do you do in an asymptomatic 25yr old for cervical cancer screening?

A

HPV DNA sequence only

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5
Q

What tests do you do in an symptomatic 25yr old for cervical cancer screening?

A

HPV DNA test and Reflex LBC
(Co-test)
F/b COLPOSCOPIC BIOPSY

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6
Q

Frequency of tests in an immunosuppressed pt for cervical cancer screening?

A

Every 3 yrs
(Every 5 yrs in normal pt)

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7
Q

Histopathology of Cervical Cancer

A

Dysplasia of columnar to squamous cells in transitional zone

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8
Q

Symptoms of Cervical cancer

A

Post-coital bleeding
Post menopausal bleeding

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9
Q

Cervical Cancer screening done in

A
  1. Vaccinated
  2. Non-vaccinated
  3. Hysterectomy with cervix portion left
  4. DES exposure - yearly
  5. Pregnancy
  6. Post-meno (give vag estrogen - stop before 3 days of trsting)
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10
Q

Screening pathway in HPV positive (not 16,18)

A

HPV + (not 16,18)
LBC - negative/LSIL
.
repeat after 1 yr
.
same result
.
repeat after 1 yr
HPV+
.
Colposcopy (2yrs)

If HPV-ve, 5 yearly screening

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11
Q

A patient had positive co-test (HPV and LBC) 1yr ago. The co-test is positive again when tested. In what cases of HPV+ (not 16,18) should colposcopy be done immediately?

A
  1. > 50yrs
  2. Aborginal or Torres island woman
  3. Screening not done for >7yrs before the initial test
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12
Q

Cervical Cancer Screening co-test positive for HPV16,18. Next step of management?

A

Colposcopic biopsy

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13
Q

Co-test unsatisfactory in Cervical Cancer Screening, when to re-test again?

A

6-12 weeks

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14
Q

Cervical Cancer Screening co-test shows HPV+(not 16,18), LBC shows HSIL. Next step is to?

a. Colposcopy
b. Re-test after 12 months

A

a. Colposcopy

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15
Q

Management of Cervical Cancer (HSIL)

A
  1. Cold knife
  2. LLETZ
    .
    Co-test after 1 yr -ve
    .
    Co-test after 1 yr -ve
    .
    Screening every 5yrs

(Negative co-test for 2 consecutive years)

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16
Q

Management of Cervical cancer LBS showing LSIS

A

Not required

17
Q

HPV Vaccine information

A

12-13yrs
male and female
GARDASIL 9 (6,11,16,18,31,33,45,52,58)
Quadrivalent GARDASIL (6,11,16,18)

18
Q

<14 yr old, with sexual history, vaccination not done. When should you do screening for cervical cancer?

a. Immediately
b. >25yrs
c. 20-24yrs

A

20-24yrs of age
(Before 25yrs as normally done)

Cervical Cancer Screening (2 decks)

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