Schizoprenia Flashcards
positive symptoms
delusions
hallucinations
disorganised thought/speech
negative symptoms
poor speech
poor motivation
social withdrawal
poor attention and memory
causes of Schizoprenia - 4
genetic and environment - affects brain development
ventricular enlargement
increased dopamine in mesolimbic pathway
developmental delay
2 diagnostic tests for Schizoprenia
DSM5
ICD-10
DSM5 criteria
2 for at least 6 months
- delusions
- hallucinations
- disorganised speech
- disorganised behaviour
- negative symptoms
ICD-10 criteria
1 of these for at least 6 months
- feeling they have enemies
- deluded perception
- thought insertion/withdrawal/broadcast
- some one else controls their actions
- someone else controls their senses
2 of:
- persistent halucinaions
- made up words/disorganised speech
- -ve symptoms
DDx
organic mental disorders
mood disorders
drug psychosis
5 types of Schizoprenia
paranoid catatonic hebephrenic residual simple schizo
paranoid Schizoprenia
delusions
auditory hallucinations
catatonic Schizoprenia
motor symptoms
heberphrenic Schizoprenia
irresponsible behaviour
inappropriate mood
simple Schizoprenia
negative symptoms
prodromal risk factors for Schizoprenia
anxiety
depression
fear they’re being watched
other risk factors for Schizoprenia
stress
decline in function
relative with Schizoprenia
2 pharmacological categories of treatment for Schizoprenia
psychotic
antipsychotic
anti psychotic treatment MOA
blocks D1/D2 receptors
what are anti psychotic good at
effective with positive symptoms
side effects of anti psychotics
extra pyramidial
anti psychotic examples
chlorpromazine
trifluoperazine
butrophenanes
chlorpromazine
when sedation needed
trifluoperazine
when no sedation needed
butrophenanes
acute
atypical anti psychotics MOA
blocks D2 more than D1
less extrapyrimidal SE
examples of atypical anti psychotics
risperidone
olanzapine
clozapine
