Schizophrenia Spectrum and Other Psychotic Disorders Flashcards
What age are males and females when psychotic disorders start?
males 15-25yr
females 25-35yr
What is the most common psychotic disorder affecting 1% of the population?
Schizophrenic
What is schizophrenic disorder?
a massive disruption of thinking, mood, and overall behavior coupled with poor filtering of stimuli
What percent of pts with schizophrenia require long term hospitalization?
50%
What 3 things causes schizophrenia?
genetic, environmental, neurochemical
Who responds more successfully to medications?
Women than man
What percent of schizophrenics have no affected parent?
80%
What are two environmental influences of schizophrenia?
- born in the winter, with maternal virus infection during the 3rd trimester
- exposure to diuretics for severe maternal HTN
What 3 neuro changes take place in a schizo brain?
- decrease glucose utilization by frontal lobe
- Ventricle enlargement
- Abnormalities in brain density and brain waves
What is the dopamine hypothesis?
Hyperactive dopamine in the mesolimbic tract leads to positive symptoms
Hypoactive dopamine in the mesocortical tract leads to negative symptoms
What creates hallucinations and delusions?
Serotonin agnosits
What can be given to improve hallucinations and delusions?
serotonin antagonists
During a psychotic episode what is intact in the patient?
memory (oriented to person, place, and time)
What characterizes schizophrenia?
at least 1 episode of psychosis and persistent disturbances of behavior, appearance, speech, and affect impairing them
When can a psychotic episode occur?
spontaneous or follow traumatic/ stressful event
What are the 5 positive symptoms?
Hallucinations Delusions Disorganized Speech Agitation Talkativeness
What are 7 negative symptoms?
diminished sociability restricted affect poverty of speech lack of motivation flat affect cognitive disturbances poor grooming
How long must schizophrenic last?
> 6 mo
What is the criteria for schizophrenic?
2 or more symptoms are present for a significant portion of time during a 1 month period
What are the 3 phases of Schizophrenia?
Prodromal
Psychotic
Residual
What 3 things are seen in the Prodromal phase?
- Still functioning in reality
- Increasing social withdrawal
- Increasing interest in religion, the occult, and philosophy
What 1 thing is seen in the Psychotic phase?
“Psychotic break” from reality
What 2 things are seen in the Residual phase?
- Period between psychotic episodes
- Negative symptoms are still present and patient is not back to “normal”
What is Alogia?
Poverty of speech- no informative information
What are delusions?
false beliefs not correctable by logic or reason
What does delusions commonly consist of?
paranoid thinking and preoccupation with the supposedly threatening behavior of others
What are somatic delusions?
delusions that revolve around issues of bodily decay or infestation